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VAMP2 cdna clone

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Catalog # MBS1270992
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
VAMP2 cdna clone
Product Name

VAMP2, cDNA Clone

Full Product Name

VAMP2 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgtctgcta ccgctgccac ggccccccct gctgccccgg ctggggaggg tggtccccct gcaccccctc caaacctcac cagtaacagg agactgcagc agacccaggc ccaggtggat gaggtggtgg acatcatgag ggtgaacgtg gacaaggtcc tggagcgaga ccagaagctg tcggagctgg acgaccgtgc agatgcactc caggcggggg cctcccagtt tgaaacaagc gcagccaagc tcaagcgcaa atactggtgg aaaaacctca agatgatgat catcttggga gtgatttgcg ccatcatcct catcatcatc atagtttact tcagcactta a
OMIM
185881
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of VAMP2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for VAMP2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
12,663 Da
NCBI Official Full Name
Homo sapiens vesicle-associated membrane protein 2 (synaptobrevin 2), mRNA
NCBI Official Synonym Full Names
vesicle associated membrane protein 2
NCBI Official Symbol
VAMP2  [Similar Products]
NCBI Official Synonym Symbols
SYB2; VAMP-2
  [Similar Products]
NCBI Protein Information
vesicle-associated membrane protein 2
UniProt Protein Name
Vesicle-associated membrane protein 2
UniProt Synonym Protein Names
Synaptobrevin-2
UniProt Gene Name
VAMP2  [Similar Products]
UniProt Synonym Gene Names
SYB2; VAMP-2  [Similar Products]
UniProt Entry Name
VAMP2_HUMAN
NCBI Summary for VAMP2
The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008]
UniProt Comments for VAMP2
VAMP2: a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. Thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Vesicle

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: clathrin-coated vesicle; cytoplasmic vesicle; cytosol; integral to plasma membrane; intracellular membrane-bound organelle; membrane; neuron projection; perinuclear region of cytoplasm; plasma membrane; secretory granule; secretory granule membrane; SNARE complex; synapse; synaptic vesicle; synaptic vesicle membrane; trans-Golgi network; vesicle; voltage-gated potassium channel complex; zymogen granule membrane

Molecular Function: calcium-dependent protein binding; calmodulin binding; phospholipid binding; protein binding; protein self-association; SNAP receptor activity; SNARE binding; syntaxin binding; syntaxin-1 binding

Biological Process: calcium ion-dependent exocytosis; cellular response to insulin stimulus; eosinophil degranulation; exocytosis; glutamate secretion; Golgi to plasma membrane protein transport; natural killer cell degranulation; neurotransmitter secretion; neutrophil degranulation; post-Golgi vesicle-mediated transport; protein complex assembly; protein transport; regulation of exocytosis; response to glucose stimulus; synaptic vesicle exocytosis; vesicle fusion; vesicle-mediated transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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