NP_001083892.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
60,105 Da
NCBI Official Full Name
vang-like protein 2-B
NCBI Official Synonym Full Names
VANGL planar cell polarity protein 2 S homeolog
NCBI Official Synonym Symbols
Ltap; lpp1; stb1; stbm; stbm1; vangl2; vangl2b; vangl2-a; vangl2-b [Similar Products]
NCBI Protein Information
vang-like protein 2-B
UniProt Protein Name
Vang-like protein 2-B
UniProt Synonym Protein Names
Protein strabismus-B; Van Gogh-like protein 2-B; Xstrabismus-B; Xstbm-B
UniProt Synonym Gene Names
UniProt Comments for vangl2-b
Has a role in non-canonical Wnt/planar cell polarity (PCP) signaling; can recruite dvl/dsh and prickle from the cytoplasm to the plasma membrane. Acts in a PCP complex to regulate the polarized assembly of fibronectrin on the surface of the mesoderm during gastrulation. Regulates convergent extension in both dorsal mesoderm and neural tissue without affecting cell fate. Regulates neural fold closure during neurulation (PubMed:12074560, PubMed:15854914). May be required for cell surface localization of fzd3 and fzd6 in the inner ear ().
Research Articles on vangl2-b
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Pathways associated with vangl2-b recombinant protein
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