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VDAC2 peptide

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Catalog # MBS425459
Unit / Price
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  0.1 mg  /  $190 +1 FREE 8GB USB
VDAC2 peptide
Product Name

VDAC2, Peptide

Full Product Name

VDAC2 Immunizing Peptide

Product Synonym Names
VDAC2; voltage-dependent anion channel 2; RP11-375G3.1; FLJ23841; VDAC2 (Internal)
Product Gene Name
Antibody/Peptide Pairs
VDAC2 peptide (MBS425459) is used for blocking the activity of VDAC2 antibody (MBS421494)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
C-DSAKSKLT RNN
OMIM
193245
Species Reactivity
Human, Mouse, Rat, Dog
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of VDAC2 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for VDAC2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
30,412 Da
NCBI Official Full Name
voltage-dependent anion-selective channel protein 2 isoform 2
NCBI Official Synonym Full Names
voltage dependent anion channel 2
NCBI Official Symbol
VDAC2  [Similar Products]
NCBI Official Synonym Symbols
NCBI Protein Information
voltage-dependent anion-selective channel protein 2
UniProt Protein Name
Voltage-dependent anion-selective channel protein 2
UniProt Synonym Protein Names
Outer mitochondrial membrane protein porin 2
UniProt Gene Name
VDAC2  [Similar Products]
UniProt Synonym Gene Names
VDAC-2; hVDAC2  [Similar Products]
UniProt Entry Name
VDAC2_HUMAN
NCBI Summary for VDAC2
This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
UniProt Comments for VDAC2
VDAC2: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation- selective. Interacts with hexokinases. Expressed in all tissues examined. Belongs to the eukaryotic mitochondrial porin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Channel, misc.; Mitochondrial

Chromosomal Location of Human Ortholog: 10q22

Cellular Component: lipid raft; mitochondrial inner membrane; mitochondrial outer membrane; mitochondrion; myelin sheath; nucleus; pore complex; synaptic vesicle

Molecular Function: nucleotide binding; porin activity; protein binding; voltage-gated anion channel activity

Biological Process: anion transport; negative regulation of protein polymerization; transmembrane transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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