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VEGFR1 recombinant protein :: Vascular Endothelial Growth Factor Receptor 1 (VEGFR1) Recombinant Protein

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Catalog # MBS2011780 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $110 +1 FREE 8GB USB
  0.05 mg  /  $185 +1 FREE 8GB USB
  0.1 mg  /  $260 +1 FREE 8GB USB
  0.2 mg  /  $315 +1 FREE 8GB USB
  0.5 mg  /  $600 +1 FREE 8GB USB
  1 mg  /  $890 +1 FREE 8GB USB
Product Name

Vascular Endothelial Growth Factor Receptor 1 (VEGFR1), Recombinant Protein

Popular Item
Also Known As

Recombinant Vascular Endothelial Growth Factor Receptor 1 (VEGFR1)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
1336
Sequence
The target protein is fused with two N-terminal Tags, His-tag and S-tag, its sequence is listed below.
MHHHHHHSSG LVPRGSGMKE TAAAKFERQH MDSPDLGTDD DDKAMADIGS EF-SRDKGLY T CRVKSGSSFR TFNTSVHVYE KGFISVKHRK QQVQETIAGK RSHRLSMKVK AFPSPEVVWL KDGVPATEKS ARYSVHGYSL IIKDVTAEDA GDYTILLGIK QSKLFRNLTA TLIVNVKPQI YEKSVSSLPS PPLYPLGSRQ VLTCTVYGIP QPTIKWLWHP CHYNHSKERN DFCFGSEESF ILDSSSNIGN RIEGITQRMM VIEGTNKTVS TLVV
Chromosome Location
Chromosome: 12; NC_005111.3 (10927827..10959880, complement). Location: 12p11
3D Structure
ModBase 3D Structure for P53767
Host
E Coli
Purity/Purification
> 95%
Form/Format
Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Organism
Rattus norvegicus (Rat)
Expression System
Prokaryotic expression
Residues
Ser303~Val524 (Accession # P53767) with two N-terminal Tags, His-tag and S-tag
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Reconstitution
Reconstitute in sterile PBS, pH7.2-pH7.4.
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
Other Notes
Small volumes of VEGFR1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
VEGFR1 recombinant protein
About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
Applications Tested/Suitable for VEGFR1 recombinant protein
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

Sequence Information of VEGFR1 recombinant protein
VEGFR1 recombinant protein Sequence Information image
VEGFR1 recombinant protein Testing Data image
NCBI/Uniprot data below describe general gene information for VEGFR1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
30.7kDa
NCBI Official Full Name
vascular endothelial growth factor receptor 1
NCBI Official Synonym Full Names
FMS-related tyrosine kinase 1
NCBI Official Symbol
NCBI Official Synonym Symbols
VEGFR-1
  [Similar Products]
NCBI Protein Information
vascular endothelial growth factor receptor 1; FLT-1; FMS-like tyrosine kinase 1; tyrosine-protein kinase receptor FLT; vascular endothelial growth factor receptor-1; Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
UniProt Protein Name
Vascular endothelial growth factor receptor 1
UniProt Synonym Protein Names
Fms-like tyrosine kinase 1; FLT-1; Tyrosine-protein kinase receptor FLT
UniProt Gene Name
UniProt Synonym Gene Names
Flt-1; Vegfr1; VEGFR-1; FLT-1  [Similar Products]
UniProt Entry Name
VGFR1_RAT
NCBI Summary for VEGFR1
tyrosine kinase receptor for vascular endothelial growth factor; may play a role in cell proliferation and cell survival [RGD, Feb 2006]
UniProt Comments for VEGFR1
VEGFR1: a receptor tyrosine kinase of the VEGFR family. Receptor for VEGF, VEGFB and PGF. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Two splice variant isoforms have been described. Isoform SFlt1 may have an inhibitory role in angiogenesis.

Protein type: EC 2.7.10.1; Kinase, protein; Protein kinase, TK; Membrane protein, integral; Protein kinase, tyrosine (receptor); TK group; VEGFR family

Cellular Component: focal adhesion; integral to plasma membrane; plasma membrane; endosome; receptor complex

Molecular Function: identical protein binding; vascular endothelial growth factor receptor activity; growth factor binding; transmembrane receptor protein tyrosine kinase activity; receptor signaling protein tyrosine kinase activity; ATP binding

Biological Process: peptidyl-tyrosine phosphorylation; activation of MAPKK activity; positive regulation of smooth muscle cell proliferation; protein amino acid autophosphorylation; chemotaxis; protein amino acid phosphorylation; positive regulation of vascular endothelial growth factor receptor signaling pathway; monocyte chemotaxis; positive regulation of MAP kinase activity; positive regulation of fibroblast proliferation; positive regulation of cell proliferation; angiogenesis; embryonic morphogenesis; cell differentiation; regulation of smooth muscle contraction; cell migration; intracellular receptor-mediated signaling pathway; positive regulation of phosphoinositide 3-kinase activity; patterning of blood vessels; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of angiogenesis; response to hypoxia; blood vessel morphogenesis; sprouting angiogenesis; vascular endothelial growth factor receptor signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway; positive regulation of cell migration
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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