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vMIP2 recombinant protein :: Viral Macrophage inflammatory Protein-2 Recombinant Protein

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Catalog # MBS144127
Unit / Price
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  0.01 mg  /  $140 +1 FREE 8GB USB
  0.05 mg  /  $205 +1 FREE 8GB USB
  1 mg  /  $1,365 +1 FREE 8GB USB
vMIP2 recombinant protein
Product Name

Viral Macrophage inflammatory Protein-2 (vMIP2), Recombinant Protein

Full Product Name

Recombinant Viral Macrophage inflammatory Protein-2

Product Synonym Names
MIP2 Viral; MIP-2 Viral Recombinant; MIP-2 Viral; Viral MIP-2; MIP2 Viral; Viral MIP2; Viral Macrophage inflammatory Protein-2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
LGASWHRPDK CCLGYQKRPL PQVLLSSWYP TSQLCSKPGV IFLTKRGRQV CADKSKDWVK KLMQQLPVTA
Host
E Coli
Purity/Purification
Greater than 97.0% as determined by RP-HPLC & SDS-PAGE.
Form/Format
Lyophilized from 1mg/ml solution containing 20mM Phospahte Buffer, pH 7.4 % 0.15M NaCl.
Sterile Filtered White lyophilized (freeze-dried) powder.
Solubility
It is recommended to reconstitute the lyophilized CXCL2 Viral in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity
Determined by the inhibitory effect on monocyte migration response to human MIP1A using a concentration range of 1 ug-10 ug/ml of viral MIP2 which will inhibit 25ng/ml of human MIP1A.
Preparation and Storage
Lyophilized MIP-2 Viral protein although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution CXCL2 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Other Notes
Small volumes of vMIP2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
vMIP2 recombinant protein
Description: MIP-2 Viral Recombinant produced in E Coli is a single,non-glycosylated, polypeptide chain containing 70 amino acids and having a molecular mass of 7.9 kDa. The MIP-2 is purified by proprietary chromatographic techniques.

Introduction: Viral MIP-2 is closely related to MIP-1alpha, show amino acid sequence similarity of about 41%. At the amino acid sequence level, Viral MIP-1 and Viral MIP-2 share 48% similarity. Viral MIP-1 and Viral MIP-2 are more closely linked to one another phylogenetically than to other human chemokines, signifying that they have gene duplication within the virus rather than by two independent gene aquisitions. Viral MIP-2 binds to the CCR3 chemokine receptor through which eotaxin and other beta chemokines activate eosinophils. Viral MIP-2 activates and chemoattract human eosinphils.
NCBI/Uniprot data below describe general gene information for vMIP2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
Molecular Weight
10,486 Da
NCBI Official Full Name
Viral macrophage inflammatory protein 2
NCBI Official Symbol
NCBI Protein Information
interleukin 8-like CC chemokine; K4; vCCL-2; vMIP-II
UniProt Protein Name
Viral macrophage inflammatory protein 2
UniProt Synonym Protein Names
Viral macrophage inflammatory protein II; vMIP-II; vMIP-1B
UniProt Gene Name
ORF K4  [Similar Products]
UniProt Synonym Gene Names
vMIP-II  [Similar Products]
UniProt Entry Name
VMI2_HHV8P
UniProt Comments for vMIP2
Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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