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WFDC1 recombinant protein :: WAP Four Disulfide Core Domain Protein 1 Recombinant Protein

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Catalog # MBS2030487 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
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  0.01 mg  /  $145 +1 FREE 8GB USB
  0.05 mg  /  $270 +1 FREE 8GB USB
  0.1 mg  /  $420 +1 FREE 8GB USB
  0.2 mg  /  $515 +1 FREE 8GB USB
  0.5 mg  /  $995 +1 FREE 8GB USB
  1 mg  /  $1,480 +1 FREE 8GB USB
SDS-Page
Product Name

WAP Four Disulfide Core Domain Protein 1 (WFDC1), Recombinant Protein

Full Product Name

Recombinant WAP Four Disulfide Core Domain Protein 1 (WFDC1)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.
MGSSHHHHH H SSGLVPRGSH MASMTGGQQM GRGSEF- QGTWEAM LPARLAEKSR AEEVAATGSR QPHADRCPPP PRTLPPGACQ ATRCQADSEC PRHRRCCYNG CAYACLEAVP PPPVLDWLVQ PKPRWLGGNG WLLDGPEEVL QAETCSTTED GAEPLLCPSG YECHILQPGD EAQGIPNHGQ CVKQRRQAEG RVLRQRLHKE YPEGDSKNVA EPGKGQQR
OMIM
605322
Host
Host: E Coli
Source: Prokaryotic expression
Purity/Purification
>95%
Form/Format
Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Concentration
6.9 (lot specific)
Predicted Molecular Mass
24.1kDa
Accurate Molecular Mass (KD)
29kDa
Endotoxin
<1.0EU per 1ug (determined by the LAL method)
Expression System
Prokaryotic expression
Tag
two N-terminal Tags, His-tag and T7-tag
Organism Species
Mus musculus (Mouse)
Fragment
Gln24~Arg208
Usage
Reconstitute in sterile PBS, pH7.2-pH7.4.
Preparation and Storage
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of WFDC1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for WFDC1 recombinant protein
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

NCBI/Uniprot data below describe general gene information for WFDC1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,977 Da
NCBI Official Full Name
WAP four-disulfide core domain protein 1 isoform 1
NCBI Official Synonym Full Names
WAP four-disulfide core domain 1
NCBI Official Symbol
WFDC1  [Similar Products]
NCBI Official Synonym Symbols
NCBI Protein Information
WAP four-disulfide core domain protein 1
UniProt Protein Name
WAP four-disulfide core domain protein 1
UniProt Synonym Protein Names
Prostate stromal protein ps20; ps20 growth inhibitor
UniProt Gene Name
WFDC1  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
WFDC1_HUMAN
NCBI Summary for WFDC1
This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. This gene is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
UniProt Comments for WFDC1
WFDC1: Has growth inhibitory activity.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 16q24.3

Cellular Component: extracellular space

Molecular Function: serine-type endopeptidase inhibitor activity

Biological Process: response to drug; negative regulation of cell growth; response to estradiol stimulus; negative regulation of epithelial cell proliferation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withWFDC1 recombinant protein
 Reference Product  PubMed Publications
 CBFA2T3 recombinant protein  >1 publications with WFDC1 and CBFA2T3
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