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WWOX shrna

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Catalog # MBS8279082
Unit / Price DISCONTINUED
WWOX shrna
Product Name

WWOX, shRNA

Also Known As

WWOX shRNA Plasmid (Mouse)

Product Synonym Names
WOX1; WW domain-containing oxidoreductase
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
414
3D Structure
ModBase 3D Structure for Q91WL8
Host
E Coli
Species Reactivity
Mouse
Specificity
WWOX shRNA Plasmid (Mouse) contains 3 different target-specific plasmids each encoding 19-23 nt (plus hairpin) shRNAs designed to knock down gene expression. Each plasmid contains a resistance gene for the selection of cells stably expressing shRNA.
Form/Format
Lyophilized Powder
Quality Control
The sequence of shRNA is guaranteed by sequencing.
Directions for Use
Resuspend lyophilized shRNA plasmid DNA in 500 ul of the deionized water. Each vial contains 50 ug of lyophilized shRNA plasmid DNA. Suitable for up to 50 transfections.
Components
We offer 3 different plasmids which knock down mouse WWOX gene specifically. Each vial contains 50 ug of lyophilized shRNA.
Preparation and Storage
Store lyophilized shRNA plasmid DNA at -20 degree C with desiccant. Stable for one year. Once resuspended, store at 4 degree C for short term storage or -80 degree C for long term storage. Avoid repeated freeze thaw cycles.
Other Notes
Small volumes of WWOX shrna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
WWOX shrna
shRNA Plasmid to inhibit WWOX expression by RNA interference
Applications Tested/Suitable for WWOX shrna
RNA interference (RNAi)
NCBI/Uniprot data below describe general gene information for WWOX. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,457 Da
NCBI Official Full Name
WW domain-containing oxidoreductase
NCBI Official Synonym Full Names
WW domain-containing oxidoreductase
NCBI Official Symbol
NCBI Official Synonym Symbols
WOX1; 5330426P09Rik; 9030416C10Rik
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NCBI Protein Information
WW domain-containing oxidoreductase
UniProt Protein Name
WW domain-containing oxidoreductase
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Comments for WWOX
Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm (). May also play a role in tumor necrosis factor (TNF)-mediated cell death. Required for normal bone development.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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