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XCL1 recombinant protein :: Lymphotactin/XCL1 Recombinant Protein

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Catalog # MBS203317
Unit / Price
  0.05 mg  /  $310 +1 FREE 8GB USB
  0.25 mg  /  $720 +1 FREE 8GB USB
SDS-Page
Product Name

Lymphotactin/XCL1, Recombinant Protein

Also Known As

Lymphotactin/XCL1, 22-114aa, Human, His tag, E Coli

Product Synonym Names
Chemokine (C motif) ligand 1; XCL1; ATAC; LPTN; LTN; SCM-1; SCM-1a; SCM1; SCYC1; Chemokine (C motif) ligand 1; Lymphotactin/XCL1; Chemokine (C motif) ligand 1 C motif chemokine 1; SCM 1 alpha; SCM1; SCYC1; Chemokine C Motif Ligand 1; Small inducible cytokine C1; Small Inducible Cytokine Subfamily C Member 1; XC chemokine ligand 1; XCL1.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
114
Sequence
MGSSHHHHHH SSGLVPRGSH MVGSEVSDKR TCVSLTTQRL PVSRIKTYTI TEGSLRAVIF ITKRGLKVCA DPQATWVRDV VRSMDRKSNT RNNMIQTKPT GTQQSTNTAV TLTG
OMIM
U23772 mRNA
3D Structure
ModBase 3D Structure for P47992
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 30% glycerol 2 mM DTT, 0.2 M NaCl.
Concentration
0.25 mg/ml (determined by Bradford assay) (lot specific)
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of XCL1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
XCL1 recombinant protein
Lymphotactin, also known as XCL1, is member of gamma or C subfamily of chemokines. It is found in high levels in spleen, thymus, intestine and peripheral blood leukocytes, and at lower levels in lung, prostate gland and ovary. The expression of lymphotactin is restricted to activated T cells such as activated CD8+ T cells and other calss IMHC restricted T cells. Since lymphotactin is produced by lymphocytes and acts on lymphocytes, it is speculated that it is a messenger in T cell chemoattraction. Recombinant human XCL1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography.
Product Categories/Family for XCL1 recombinant protein
Applications Tested/Suitable for XCL1 recombinant protein
SDS-PAGE

NCBI/Uniprot data below describe general gene information for XCL1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
12.5 kDa (114aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher) [Similar Products]
NCBI Official Full Name
lymphotactin
NCBI Official Synonym Full Names
X-C motif chemokine ligand 1
NCBI Official Symbol
NCBI Official Synonym Symbols
LTN; ATAC; LPTN; SCM1; SCM-1; SCM1A; SCYC1; SCM-1a
  [Similar Products]
NCBI Protein Information
lymphotactin
UniProt Protein Name
Lymphotactin
UniProt Synonym Protein Names
ATAC; C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; SCM-1-alpha; Small-inducible cytokine C1; XC chemokine ligand 1
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
LTN; SCYC1  [Similar Products]
NCBI Summary for XCL1
This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1. [provided by RefSeq, Sep 2014]
UniProt Comments for XCL1
Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
Product References and Citations for XCL1 recombinant protein
Yoshida T., et al. (1996). FEBS Lett. 395 (1):82-8.; Kennedy J., et al. (1995). J Immunol. 155 (1):203-9.;

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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