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XRN2 elisa kit :: Human 5'-3'Exoribonuclease 2 (XRN2) ELISA Kit

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Catalog # MBS9312769
Unit / Price
  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
XRN2 elisa kit
Product Name

5'-3'Exoribonuclease 2 (XRN2), ELISA Kit

Popular Item
Full Product Name

Human 5'-3'Exoribonuclease 2 (XRN2) ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Chromosome Location
Chromosome: 20; NC_000020.10 (21283942..21370463). Location: 20p11.2-p11.1
OMIM
608851
3D Structure
ModBase 3D Structure for Q9H0D6
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of XRN2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forXRN2purchase
MBS9312769 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 5'-3'Exoribonuclease 2 (XRN2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing XRN2. The ELISA analytical biochemical technique of the MBS9312769 kit is based on XRN2 antibody-XRN2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect XRN2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, XRN2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Sample Manual Insert of MBS9312769. Click to request current manual
NCBI/Uniprot data below describe general gene information for XRN2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
108,582 Da
NCBI Official Full Name
XRN2 protein
NCBI Official Synonym Full Names
5'-3' exoribonuclease 2
NCBI Official Symbol
NCBI Protein Information
5'-3' exoribonuclease 2; DHP protein; Dhm1-like protein (mouse homolog)
UniProt Protein Name
5'-3' exoribonuclease 2
UniProt Synonym Protein Names
DHM1-like protein
UniProt Gene Name
UniProt Synonym Gene Names
DHP protein  [Similar Products]
UniProt Entry Name
XRN2_HUMAN
NCBI Summary for XRN2
This gene shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The yeast gene is involved in homologous recombination and RNA metabolism, such as RNA synthesis and RNA trafficking. Complementation studies show that Dhm1 has a similar function in mouse as dhp1. The function of the human gene has not yet been determined. Transcript variants encoding different isoforms have been noted for this gene; however, their full-length nature is not known. [provided by RefSeq, Jul 2008]
UniProt Comments for XRN2
XRN2: Possesses 5'->3' exoribonuclease activity. May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Cell development/differentiation; Nucleolus; Ribonuclease; RNA processing; EC 3.1.13.-

Chromosomal Location of Human Ortholog: 20p11.2-p11.1

Cellular Component: membrane; nucleolus; nucleus

Molecular Function: 5'-3' exonuclease activity; 5'-3' exoribonuclease activity; nuclease activity; zinc ion binding

Biological Process: RNA processing; regulation of transcription, DNA-dependent; RNA metabolic process; RNA catabolic process; spermatogenesis; cell growth; DNA catabolic process, exonucleolytic; mRNA processing; transcription termination
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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