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XRN2 recombinant protein :: 5'-3' exoribonuclease 2 (XRN2) Recombinant Protein

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Catalog # MBS1319027
Unit / Price
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  0.05 mg (E-Coli)  /  $545 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $705 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $730 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $805 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $860 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $955 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,070 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,080 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,100 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,130 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,565 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,625 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,675 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,095 +2 FREE 8GB USB
XRN2 recombinant protein
Product Name

5'-3' exoribonuclease 2 (XRN2), Recombinant Protein

Full Product Name

Recombinant Human 5'-3' exoribonuclease 2 (XRN2) , partial

Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
396-545. Partial.
Sequence
VGEVEDSIFK KRKDDEDSFR RRQKEKRKRM KRDQPAFTPS GILTPHALGS RNSPGSQVAS NPRQAAYEMR MQNNSSPSIS PNTSFTSDGS PSPLGGIKRK AEDSDSEPEP EDNVRLWEAG WKQRYYKNKF DVDAADEKFR RKVVQSYVEG
OMIM
608851
3D Structure
ModBase 3D Structure for Q9H0D6
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of XRN2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for XRN2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
99,962 Da
NCBI Official Full Name
5'-3' exoribonuclease 2 isoform 1
NCBI Official Synonym Full Names
5'-3' exoribonuclease 2
NCBI Official Symbol
NCBI Protein Information
5'-3' exoribonuclease 2
UniProt Protein Name
5'-3' exoribonuclease 2
UniProt Synonym Protein Names
DHM1-like protein; DHP protein
UniProt Gene Name
UniProt Synonym Gene Names
DHP protein  [Similar Products]
NCBI Summary for XRN2
This gene encodes a 5'-3' exonuclease that promotes transcription termination at cotranscriptional cleavage sites. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
UniProt Comments for XRN2
Possesses 5'->3' exoribonuclease activity (). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites (PubMed:21700224).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with XRN2 recombinant protein
Diseases associated with XRN2 recombinant protein
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