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YBX1 recombinant protein :: Nuclease-sensitive element-binding protein 1 (YBX1) Recombinant Protein

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Catalog # MBS958394
Unit / Price
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  0.05 mg (E-Coli)  /  $730 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $835 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $985 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,065 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,075 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,125 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,280 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,305 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,540 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,630 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,005 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,025 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,120 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,105 +3 FREE 8GB USB
YBX1 recombinant protein
Product Name

Nuclease-sensitive element-binding protein 1 (YBX1), Recombinant Protein

Popular Item
Full Product Name

Recombinant Human Nuclease-sensitive element-binding protein 1 (YBX1)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS958394 COA
Sequence Positions
2-324\naa, Full Length of Mature Protein
Sequence
SSEAETQQPP AAPPAAPALS AADTKPGTTG SGAGSGGPGG LTSAAPAGGD KKVIATKVLG TVKWFNVRNG YGFINRNDTK EDVFVHQTAI KKNNPRKYLR SVGDGETVEF DVVEGEKGAE AANVTGPGGV PVQGSKYAAD RNHYRRYPRR RGPPRNYQQN YQNSESGEKN EGSESAPEGQ AQQRRPYRRR RFPPYYMRRP YGRRPQYSNP PVQGEVMEGA DNQGAGEQGR PVRQNMYRGY RPRFRRGPPR QRQPREDGNE EDKENQGDET QGQQPPQRRY RRNFNYRRRR PENPKPQDGK ETKAADPPAE NSSAPEAEQG GAE
OMIM
154030
3D Structure
ModBase 3D Structure for P67809
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of YBX1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for YBX1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
35,924 Da
NCBI Official Full Name
nuclease-sensitive element-binding protein 1
NCBI Official Synonym Full Names
Y-box binding protein 1
NCBI Official Symbol
NCBI Official Synonym Symbols
YB1; BP-8; CSDB; DBPB; YB-1; CBF-A; CSDA2; EFI-A; NSEP1; NSEP-1; MDR-NF1
  [Similar Products]
NCBI Protein Information
nuclease-sensitive element-binding protein 1
UniProt Protein Name
Nuclease-sensitive element-binding protein 1
UniProt Synonym Protein Names
CCAAT-binding transcription factor I subunit A; CBF-A; DNA-binding protein B; DBPB; Enhancer factor I subunit A; EFI-A; Y-box transcription factor; Y-box-binding protein 1; YB-1
UniProt Gene Name
UniProt Synonym Gene Names
NSEP1; YB1; CBF-A; DBPB; EFI-A; YB-1  [Similar Products]
NCBI Summary for YBX1
This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Sep 2015]
UniProt Comments for YBX1
Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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