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YWHAQ recombinant protein :: 14-3-3, tau Recombinant Protein

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Catalog # MBS636521
Unit / Price
  0.05 mg  /  $470 +1 FREE 8GB USB
  0.1 mg  /  $705 +1 FREE 8GB USB
YWHAQ recombinant protein
Product Name

14-3-3, tau (YWHAQ), Recombinant Protein

Also Known As

14-3-3, tau (YWHAQ, 1C5, HS1, Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, theta Polypeptide), Recombinant, Human

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MEKTELIQKA KLAEQAERYD DMATCMKAVT EQGAELSNEE RNLLSVAYKN VVGGRRSAWR
VISSIE QKTD TSDKKLQLIK DYREKVESEL RSICTTVLEL LDKYLIANAT NPESKVFYLK
MKGDYF RYLA EVACGDDRKQ TIDNSQGAYQ EAFDISKKEM QPTHPIRLGL ALNFSVFYYE
ILNNPE LACT LAKTAFDEAI AELDTLNEDS YKDSTLIMQL LRDNLTLWTS DSAGEECDAA
EGAEN
Chromosome Location
Chromosome: 2; NC_000002.11 (9724096..9771184, complement). Location: 2p25.1
OMIM
609009
3D Structure
ModBase 3D Structure for P27348
Purity/Purification
Highly Purified
~95% by SDS-PAGE. Purified by chromatography techniques.
Form/Format
Supplied as a liquid in 20mM Tris pH7.5
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of YWHAQ recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
YWHAQ recombinant protein
The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms that have been identified in mammals. The 14-3-3 tau, a subtype of the 14-3-3 family of proteins, was found in T Cells, brain and testes. This 14-3-3 tau is upregulated in patients with amyotrophic lateral sclerosis. Recombinant human YWHAQ was expressed in E. coli and purified by using conventional chromatography techniques.
Application Notes for YWHAQ recombinant protein
Suitable for use in Western Blot.
NCBI/Uniprot data below describe general gene information for YWHAQ. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
NCBI Official Full Name
14-3-3 protein theta
NCBI Official Synonym Full Names
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
NCBI Official Symbol
YWHAQ  [Similar Products]
NCBI Official Synonym Symbols
1C5; HS1; 14-3-3
  [Similar Products]
NCBI Protein Information
14-3-3 protein theta; 14-3-3 protein tau; 14-3-3 protein T-cell
UniProt Protein Name
14-3-3 protein theta
UniProt Synonym Protein Names
14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1
Protein Family
UniProt Gene Name
YWHAQ  [Similar Products]
UniProt Entry Name
1433T_HUMAN
NCBI Summary for YWHAQ
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
UniProt Comments for YWHAQ
14-3-3 theta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Associates with c-BCR and BCR-Abl.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 2p25.1

Cellular Component: cytoplasmic vesicle membrane; focal adhesion; membrane; cytoplasm; cytosol

Molecular Function: protein domain specific binding; protein binding; protein N-terminus binding

Biological Process: substantia nigra development; apoptosis; small GTPase mediated signal transduction; negative regulation of transcription, DNA-dependent; protein targeting
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withYWHAQ recombinant protein
 Reference Product  PubMed Publications
 BAD recombinant protein  >1 publications with YWHAQ and BAD
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