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ZYX recombinant protein :: Zyxin (ZYX) Recombinant Protein

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Catalog # MBS969633
Unit / Price
Scan QR to view Datasheet
  0.01 mg (Mammalian-Cell)  /  $225 +1 FREE 8GB USB
  0.02 mg (Mammalian-Cell)  /  $335 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $635 +1 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $880 +1 FREE 8GB USB
SDS-Page
Product Name

Zyxin (ZYX), Recombinant Protein

Popular Item
Full Product Name

Recombinant Human Zyxin (ZYX)

Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-572aa; Full Length of Mature Protein
Sequence
AAPRPSPAIS VSVSAPAFYA PQKKFGPVVA PKPKVNPFRP GDSEPPPAPG AQRAQMGRVG EIPPPPPEDF PLPPPPLAGD GDDAEGALGG AFPPPPPPIE ESFPPAPLEE EIFPSPPPPP EEEGGPEAPI PPPPQPREKV SSIDLEIDSL SSLLDDMTKN DPFKARVSSG YVPPPVATPF SSKSSTKPAA GGTAPLPPWK SPSSSQPLPQ VPAPAQSQTQ FHVQPQPQPK PQVQLHVQSQ TQPVSLANTQ PRGPPASSPA PAPKFSPVTP KFTPVASKFS PGAPGGSGSQ PNQKLGHPEA LSAGTGSPQP PSFTYAQQRE KPRVQEKQHP VPPPAQNQNQ VRSPGAPGPL TLKEVEELEQ LTQQLMQDME HPQRQNVAVN ELCGRCHQPL ARAQPAVRAL GQLFHIACFT CHQCAQQLQG QQFYSLEGAP YCEGCYTDTL EKCNTCGEPI TDRMLRATGK AYHPHCFTCV VCARPLEGTS FIVDQANRPH CVPDYHKQYA PRCSVCSEPI MPEPGRDETV RVVALDKNFH MKCYKCEDCG KPLSIEADDN GCFPLDGHVL CRKCHTARAQ T
OMIM
602002
3D Structure
ModBase 3D Structure for Q15942
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Production Note
Special Offer: The Mammalian-Cell host-expressed protein is manufactured from a stock plasmid containing the protein gene. Mammalian-Cellhost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The Mammalian-Cell host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select Mammalian-Cell host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ZYX recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ZYX recombinant protein
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.

ZYX recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for ZYX. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
45,075 Da
NCBI Official Full Name
zyxin
NCBI Official Synonym Full Names
zyxin
NCBI Official Symbol
NCBI Official Synonym Symbols
ESP-2; HED-2
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NCBI Protein Information
zyxin
UniProt Protein Name
Zyxin
UniProt Synonym Protein Names
Zyxin-2
Protein Family
UniProt Gene Name
NCBI Summary for ZYX
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008]
UniProt Comments for ZYX
Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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