Hamster HNRNPAB ELISA Kit – Cat# MBS015641

Hnrnp-K (HNRNPAB) ELISA Kit for Hamster

Name: Hamster HNRNPAB ELISA Kit; Hnrnp-K; MyBioSource
Brand: MyBioSource
SKU: MBS015641
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS015641

Introduction: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Hnrnp-K (HNRNPAB), ELISA Kit

Full Product Name

Hamster Hnrnp-K ELISA Kit

Product Gene Name

HNRNPAB elisa kit

Species Reactivity

Hamster

Samples

Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids

Detection Range

0.25 ng/ml ~ 8 ng/ml.

Sensitivity

0.1 ng/ml.

Specificity

This kit recognizes recombinant and natural Human HNRNPAB, no significant cross-reactivity or interference was observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) are less than 15%.

Intra-assay Precision

Intra-assay CV (%) are less than 15%.

Molecular Weight

36,225 Da

Chromosome Location

Chromosome: 5; NC_000005.9 (177631508..177638184). Location: 5q35.3

OMIM

602688

3D Structure

ModBase 3D Structure for Q99729

Intended Uses

This ELISA kit is intended for laboratory in vitro research use only, not for drug, household or other use! The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm by a spectrophotometer. In order to measure the concentration of Human HNRNPAB in the sample, this ELISA kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versus Human HNRNPAB concentration. The concentration of Human HNRNPAB in the samples is then determined by comparing the O.D. of the samples to the standard curve.

Other Notes

Small volumes of HNRNPAB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HNRNPAB purchase

MBS015641 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Hnrnp-K (HNRNPAB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HNRNPAB. The ELISA analytical biochemical technique of the MBS015641 kit is based on HNRNPAB antibody-HNRNPAB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HNRNPAB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HNRNPAB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for HNRNPAB. It may not necessarily be applicable to this product.

NCBI GI #

158523286

NCBI GeneID

3182

NCBI Accession #

Q99729.2

UniProt Primary Accession #

Q99729

UniProt Secondary Accession #

Q04150; Q8N7U3; Q9BQ99; B3KNN5; D3DWP7

UniProt Related Accession #

Q99729

NCBI Official Full Name

Heterogeneous nuclear ribonucleoprotein A/B

NCBI Official Synonym Full Names

heterogeneous nuclear ribonucleoprotein A/B

NCBI Official Symbol

HNRNPAB

NCBI Official Synonym Symbols

ABBP1; HNRPAB

UniProt Protein Name

Heterogeneous nuclear ribonucleoprotein A/B

UniProt Synonym Protein Names

APOBEC1-binding protein 1

Protein Family

Heterogeneous nuclear ribonucleoprotein

UniProt Gene Name

HNRNPAB

UniProt Synonym Gene Names

ABBP1; HNRPAB; hnRNP A/B; ABBP-1

UniProt Entry Name

ROAA_HUMAN

NCBI Protein Information

heterogeneous nuclear ribonucleoprotein A/B; ABBP-1; hnRNP A/B; hnRNP type A/B protein; APOBEC1-binding protein 1; apobec-1 binding protein 1; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1-binding protein 1

NCBI Summary for HNRNPAB

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for HNRNPAB

hnRNP A/B: a single-stranded RNA binding protein with two RNA-recognition (RRM) domains. Has a high affinity for G- rich and U-rich regions of hnRNA. Also binds to APOB mRNA transcripts around the RNA editing site. Interacts with APOBEC1. Observed in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. A member of the RNA recognition motif (RRM) family. Four isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 5q35.3

Cellular Component: nucleoplasm; cytoplasm; ribonucleoprotein complex; nucleus

Molecular Function: mRNA binding; sequence-specific DNA binding; RNA binding; nucleotide binding; transcription factor activity

Biological Process: positive regulation of transcription, DNA-dependent; epithelial to mesenchymal transition; negative regulation of transcription from RNA polymerase II promoter

Research Articles on HNRNPAB

1. physical association of p63alpha and ABBP1 led to a specific shift of FGFR-2 alternative splicing toward the K-SAM isoform essential for epithelial differentiation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HNRNPAB elisa kit

Reference Product	PubMed Publications
APOB elisa kit	>2 publications with HNRNPAB and APOB
TP63 elisa kit	>1 publications with HNRNPAB and TP63

Pathways associated with HNRNPAB elisa kit

Products by Pathway	Pathway Diagram
MRNA Processing Pathway antibodies	MRNA Processing Pathway Diagram

Diseases associated with HNRNPAB elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>1 publications with HNRNPAB and Neoplasms
Cardiovascular Diseases Antibodies	>1 publications with HNRNPAB and Cardiovascular Diseases
Brain Diseases Antibodies	>1 publications with HNRNPAB and Brain Diseases
Inflammation Antibodies	>1 publications with HNRNPAB and Inflammation

Organs/Tissues associated with HNRNPAB elisa kit

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>1 publications with HNRNPAB and Skin
Brain Antibodies	>1 publications with HNRNPAB and Brain