Human CYSLTR2 ELISA Kit – Cat# MBS020113

Cysteinyl Leukotriene Receptor 2 (CYSLTR2) ELISA Kit for Human

Name: Human CYSLTR2 ELISA Kit; Cysteinyl Leukotriene Receptor 2; MyBioSource
Brand: MyBioSource
SKU: MBS020113
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS020113

MBS020113 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cysteinyl Leukotriene Receptor 2 (CYSLTR2) ELISA Kit target analytes in biological samples. The concentration gradients of the… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Cysteinyl Leukotriene Receptor 2 (CYSLTR2), ELISA Kit

Full Product Name

Human Cysteinyl Leukotriene Receptor 2 ELISA Kit

Product Gene Name

CYSLTR2 elisa kit

Species Reactivity

Human

Assay Type

Sandwich

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

39,635 Da

Chromosome Location

Chromosome: 13; NC_000013.10 (49280951..49283498). Location: 13q14.2

OMIM

605666

3D Structure

ModBase 3D Structure for Q9NS75

Other Notes

Small volumes of CYSLTR2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CYSLTR2. It may not necessarily be applicable to this product.

NCBI GI #

37362411

NCBI GeneID

57105

NCBI Accession #

AAQ91330.1

UniProt Primary Accession #

Q9NS75

UniProt Secondary Accession #

Q9HCQ2

UniProt Related Accession #

Q9NS75

NCBI Official Full Name

cysteinyl leukotriene receptor 2

NCBI Official Synonym Full Names

cysteinyl leukotriene receptor 2

NCBI Official Symbol

CYSLTR2

NCBI Official Synonym Symbols

HG57; CYSLT2; HPN321; CYSLT2R; KPG_011; hGPCR21; PSEC0146

UniProt Protein Name

Cysteinyl leukotriene receptor 2

UniProt Synonym Protein Names

G-protein coupled receptor GPCR21; hGPCR21; G-protein coupled receptor HG57; HPN321

Protein Family

Cysteinyl leukotriene receptor

UniProt Gene Name

CYSLTR2

UniProt Synonym Gene Names

CYSLT2; CYSLT2R; CysLTR2; hGPCR21

UniProt Entry Name

CLTR2_HUMAN

NCBI Protein Information

cysteinyl leukotriene receptor 2; G protein-coupled receptor; G-protein coupled receptor HG57; G-protein coupled receptor GPCR21; cysteinyl leukotriene CysLT2 receptor

NCBI Summary for CYSLTR2

The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems. [provided by RefSeq, Jul 2008]

UniProt Comments for CYSLTR2

CYSLTR2: Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q14.2

Cellular Component: integral to membrane; plasma membrane

Molecular Function: protein binding; cysteinyl leukotriene receptor activity; leukotriene receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of angiogenesis; immune response

Research Articles on CYSLTR2

1. increased expression in tonsillar tissues of Chinese children with sleep-disordered breathing

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CYSLTR2 elisa kit

Reference Product	PubMed Publications
CYSLTR1 elisa kit	>14 publications with CYSLTR2 and CYSLTR1
TBXA2R elisa kit	>2 publications with CYSLTR2 and TBXA2R
GPR17 elisa kit	>1 publications with CYSLTR2 and GPR17

Pathways associated with CYSLTR2 elisa kit

Products by Pathway	Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Eicosanoid Ligand-binding Receptors Pathway antibodies	Eicosanoid Ligand-binding Receptors Pathway Diagram
Endothelins Pathway antibodies	Endothelins Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram

Diseases associated with CYSLTR2 elisa kit

Disease Name	Pubmed Publications
Asthma Antibodies	>17 publications with CYSLTR2 and Asthma
Inflammation Antibodies	>6 publications with CYSLTR2 and Inflammation
Rhinitis Antibodies	>4 publications with CYSLTR2 and Rhinitis
Drug Hypersensitivity Antibodies	>3 publications with CYSLTR2 and Drug Hypersensitivity
Asthma, Aspirin-Induced Antibodies	>3 publications with CYSLTR2 and Asthma, Aspirin-Induced
Urticaria Antibodies	>2 publications with CYSLTR2 and Urticaria
Neoplasms Antibodies	>1 publications with CYSLTR2 and Neoplasms
Pain Antibodies	>1 publications with CYSLTR2 and Pain
Eosinophilia Antibodies	>1 publications with CYSLTR2 and Eosinophilia
Cardiovascular Diseases Antibodies	>1 publications with CYSLTR2 and Cardiovascular Diseases

Organs/Tissues associated with CYSLTR2 elisa kit

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>2 publications with CYSLTR2 and Muscle
Connective Tissue Antibodies	>1 publications with CYSLTR2 and Connective Tissue
Placenta Antibodies	>1 publications with CYSLTR2 and Placenta
Brain Antibodies	>1 publications with CYSLTR2 and Brain