Early Growth Response Protein 1 (EGR1) ELISA Kit for Human

Name: Human EGR1 ELISA Kit; Early Growth Response Protein 1; MyBioSource
Brand: MyBioSource
SKU: MBS032199
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS032199

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of EGR1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates,… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Early Growth Response Protein 1 (EGR1), ELISA Kit

Full Product Name

Human Early Growth Response Protein 1 ELISA Kit

Product Gene Name

EGR1 elisa kit

Species Reactivity

Human

Assay Type

Sandwich

Samples

Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

Detection Range

3.12 ng/ml - 100 ng/ml.

Sensitivity

1.0ng/ml.

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

57,507 Da

Chromosome Location

Chromosome: 5; NC_000005.9 (137801181..137805004). Location: 5q31.1

OMIM

128990

3D Structure

ModBase 3D Structure for P18146

Other Notes

Small volumes of EGR1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EGR1 purchase

MBS032199 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Early Growth Response Protein 1 (EGR1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing EGR1. The ELISA analytical biochemical technique of the MBS032199 kit is based on EGR1 antibody-EGR1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect EGR1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, EGR1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for EGR1. It may not necessarily be applicable to this product.

NCBI GI #

4503493

NCBI GeneID

1958

NCBI Accession #

NP_001955.1

UniProt Primary Accession #

P18146

UniProt Related Accession #

P18146

GenBank Nucleotide #

NM_001964.2

NCBI Official Full Name

early growth response protein 1

NCBI Official Synonym Full Names

early growth response 1

NCBI Official Symbol

EGR1

NCBI Official Synonym Symbols

TIS8; AT225; G0S30; NGFI-A; ZNF225; KROX-24; ZIF-268

UniProt Protein Name

Early growth response protein 1

UniProt Synonym Protein Names

AT225; Nerve growth factor-induced protein A; NGFI-A; Transcription factor ETR103; Transcription factor Zif268; Zinc finger protein 225; Zinc finger protein Krox-24

Protein Family

Early growth response protein

UniProt Gene Name

EGR1

UniProt Synonym Gene Names

KROX24; ZNF225; EGR-1; NGFI-A

UniProt Entry Name

EGR1_HUMAN

NCBI Protein Information

early growth response protein 1; EGR-1; zinc finger protein 225; transcription factor ETR103; transcription factor Zif268; zinc finger protein Krox-24; nerve growth factor-induced protein A

NCBI Summary for EGR1

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. [provided by RefSeq, Jul 2008]

UniProt Comments for EGR1

EGR1: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation. By growth factors. Belongs to the EGR C2H2-type zinc-finger protein family.

Protein type: DNA-binding; Transcription factor; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: histone acetyltransferase binding; protein binding; DNA binding; sequence-specific DNA binding; metal ion binding; double-stranded DNA binding; transcription factor activity; transcription factor binding

Biological Process: response to nutrient levels; circadian rhythm; regulation of long-term neuronal synaptic plasticity; transcription from RNA polymerase II promoter; cytokine and chemokine mediated signaling pathway; positive regulation of transcription, DNA-dependent; response to amphetamine; negative regulation of transcription from RNA polymerase II promoter; response to cocaine; BMP signaling pathway; response to ethanol; learning and/or memory; cellular response to insulin stimulus; positive regulation of neuron apoptosis; response to glucose stimulus; oligodendrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; response to electrical stimulus; T cell differentiation; regulation of protein sumoylation; negative regulation of apoptosis

Research Articles on EGR1

1. Glucose and TNF-alpha increased Egr-1 expressionvia ERK1/2 activation in endothelial cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EGR1 elisa kit

Reference Product	PubMed Publications
FOS elisa kit	>574 publications with EGR1 and FOS
JUN elisa kit	>501 publications with EGR1 and JUN
NAB2 elisa kit	>46 publications with EGR1 and NAB2
ELK1 elisa kit	>44 publications with EGR1 and ELK1
PTEN elisa kit	>28 publications with EGR1 and PTEN
NAB1 elisa kit	>26 publications with EGR1 and NAB1
TP53 elisa kit	>16 publications with EGR1 and TP53
SNAI1 elisa kit	>1 publications with EGR1 and SNAI1
NFATC1 elisa kit	>1 publications with EGR1 and NFATC1
NFATC2 elisa kit	>1 publications with EGR1 and NFATC2

Pathways associated with EGR1 elisa kit

Products by Pathway	Pathway Diagram
BDNF Signaling Pathway antibodies	BDNF Signaling Pathway Diagram
Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies	Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Downstream Signaling In Naive CD8+ T Cells Pathway antibodies	Downstream Signaling In Naive CD8+ T Cells Pathway Diagram
ErbB1 Downstream Signaling Pathway antibodies	ErbB1 Downstream Signaling Pathway Diagram
Glucocorticoid Receptor Regulatory Network Pathway antibodies	Glucocorticoid Receptor Regulatory Network Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Insulin Signaling Pathway antibodies	Insulin Signaling Pathway Diagram

Diseases associated with EGR1 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>515 publications with EGR1 and Neoplasms
Nervous System Diseases Antibodies	>159 publications with EGR1 and Nervous System Diseases
Inflammation Antibodies	>141 publications with EGR1 and Inflammation
Cardiovascular Diseases Antibodies	>129 publications with EGR1 and Cardiovascular Diseases
Necrosis Antibodies	>125 publications with EGR1 and Necrosis
Brain Diseases Antibodies	>104 publications with EGR1 and Brain Diseases
Drug Toxicity Antibodies	>79 publications with EGR1 and Drug Toxicity
Ischemia Antibodies	>67 publications with EGR1 and Ischemia
Prostatic Neoplasms Antibodies	>57 publications with EGR1 and Prostatic Neoplasms
Liver Diseases Antibodies	>49 publications with EGR1 and Liver Diseases

Organs/Tissues associated with EGR1 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>720 publications with EGR1 and Brain
Blood Antibodies	>376 publications with EGR1 and Blood
Nerve Antibodies	>259 publications with EGR1 and Nerve
Vascular Antibodies	>229 publications with EGR1 and Vascular
Muscle Antibodies	>187 publications with EGR1 and Muscle
Lung Antibodies	>122 publications with EGR1 and Lung
Kidney Antibodies	>120 publications with EGR1 and Kidney
Liver Antibodies	>114 publications with EGR1 and Liver
Heart Antibodies	>93 publications with EGR1 and Heart
Bone Antibodies	>90 publications with EGR1 and Bone