Distal Less Homeobox 5 (DLX5) ELISA Kit for Human

Name: Human DLX5 ELISA Kit; Distal Less Homeobox 5; MyBioSource
Brand: MyBioSource
SKU: MBS036545
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS036545

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of DLX5 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Distal Less Homeobox 5 (DLX5), ELISA Kit

Full Product Name

Human Distal Less Homeobox 5 ELISA Kit

Product Gene Name

DLX5 elisa kit

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Samples

undiluted original Human body fluids, tissue homogenates, secretions or feces samples

Detection Range

0.625 ng/ml - 20 ng/mL

Sensitivity

0.1 ng/mL

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Other Notes

Small volumes of DLX5 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DLX5 purchase

MBS036545 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Distal Less Homeobox 5 (DLX5) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing DLX5. The ELISA analytical biochemical technique of the MBS036545 kit is based on DLX5 antibody-DLX5 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DLX5 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DLX5. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for DLX5. It may not necessarily be applicable to this product.

NCBI GI #

1620524

NCBI Accession #

AAC52843.1

NCBI Official Full Name

Dlx5

Protein Family

Homeobox protein

UniProt Comments for DLX5

DLX5: Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding. Defects in DLX5 are the cause of split-hand/foot malformation type 1, with sensorineural hearing loss (SHFM1D). A disease characterized by the association of split- hand/foot malformation with deafness. Split-hand/foot malformation is a limb malformation involving the central rays of the autopod and presenting with syndactyly, median clefts of the hands and feet, and aplasia and/or hypoplasia of the phalanges, metacarpals, and metatarsals. Some patients have been found to have mental retardation, ectodermal and craniofacial findings, and orofacial clefting. Belongs to the distal-less homeobox family.

Protein type: DNA-binding; Transcription factor

Cellular Component: nuclear chromatin; cytoplasm; nucleus

Molecular Function: protein binding; DNA binding; sequence-specific DNA binding

Biological Process: transcription from RNA polymerase II promoter; axon guidance; ossification; inner ear morphogenesis; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; multicellular organismal development; olfactory pit development; ear development; palate development; BMP signaling pathway; osteoblast differentiation; cell proliferation; positive regulation of osteoblast differentiation; regulation of transcription, DNA-dependent; epithelial cell differentiation; axonogenesis; anatomical structure formation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of epithelial cell proliferation; endochondral ossification; embryonic limb morphogenesis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.