Dermcidin (DCD) ELISA Kit for Human

Name: Human DCD ELISA Kit; Dermcidin; MyBioSource
Brand: MyBioSource
SKU: MBS062371
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS062371

Background: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used to determine the level of DCD (hereafter termed "analyte") in undiluted original… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Dermcidin (DCD), ELISA Kit

Full Product Name

Human Dermcidin ELISA Kit

Product Gene Name

DCD elisa kit

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Detection Range

0.25ng/ml-8ng/ml

Sensitivity

0.1ng/ml

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Molecular Weight

11,284 Da

OMIM

606634

3D Structure

ModBase 3D Structure for P81605

Other Notes

Small volumes of DCD elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DCD purchase

MBS062371 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Dermcidin (DCD) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing DCD. The ELISA analytical biochemical technique of the MBS062371 kit is based on DCD antibody-DCD antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DCD antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DCD. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for DCD. It may not necessarily be applicable to this product.

NCBI GI #

16751921

NCBI GeneID

117159

NCBI Accession #

NP_444513.1

UniProt Primary Accession #

P81605

UniProt Secondary Accession #

P58461; Q53YJ2; A5JHP2; A5JHP3

UniProt Related Accession #

P81605

GenBank Nucleotide #

NM_053283.3

NCBI Official Full Name

dermcidin isoform 1 preproprotein

NCBI Official Synonym Full Names

dermcidin

NCBI Official Symbol

DCD

NCBI Official Synonym Symbols

PIF; AIDD; DSEP; HCAP; DCD-1

UniProt Protein Name

Dermcidin

UniProt Synonym Protein Names

Preproteolysin

Protein Family

Bifunctional D-cysteine desulfhydrase/1-aminocyclopropane-1-carboxylate deaminase

UniProt Gene Name

DCD

UniProt Synonym Gene Names

AIDD; DSEP

UniProt Entry Name

DCD_HUMAN

NCBI Protein Information

dermcidin; preproteolysin; survival promoting peptide; proteolysis inducing factor; diffusible survival/evasion peptide

NCBI Summary for DCD

This gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

UniProt Comments for DCD

DCD: DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; EC 3.4.-.-; Secreted

Chromosomal Location of Human Ortholog: 12q13.1

Cellular Component: extracellular region

Molecular Function: peptidase activity

Biological Process: killing of cells of another organism; defense response to bacterium; proteolysis; defense response to fungus

Research Articles on DCD

1. Crystal structure and functional mechanism of a human antimicrobial membrane channel

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with DCD elisa kit

Reference Product	PubMed Publications
UBC elisa kit	>2 publications with DCD and UBC
CAMP elisa kit	>1 publications with DCD and CAMP

Diseases associated with DCD elisa kit

Disease Name	Pubmed Publications
Ischemia Antibodies	>191 publications with DCD and Ischemia
Cardiovascular Diseases Antibodies	>153 publications with DCD and Cardiovascular Diseases
Liver Failure Antibodies	>49 publications with DCD and Liver Failure
Kidney Diseases Antibodies	>42 publications with DCD and Kidney Diseases
Necrosis Antibodies	>39 publications with DCD and Necrosis
Inflammation Antibodies	>24 publications with DCD and Inflammation
Renal Insufficiency Antibodies	>21 publications with DCD and Renal Insufficiency
Memory Disorders Antibodies	>21 publications with DCD and Memory Disorders
Pain Antibodies	>19 publications with DCD and Pain
Fibrosis Antibodies	>18 publications with DCD and Fibrosis

Organs/Tissues associated with DCD elisa kit

Organ/Tissue Name	Pubmed Publications
Uncharacterized Tissue Antibodies	>1 publications with DCD and Uncharacterized Tissue