Cystatin 3 (CST3) ELISA Kit for Human

Name: Human CST3 ELISA Kit; Cystatin 3; MyBioSource
Brand: MyBioSource
SKU: MBS087116
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS087116

Background: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used to determine the level of CST3 (hereafter termed "analyte") in undiluted original… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Cystatin 3 (CST3), ELISA Kit

Full Product Name

Human Cystatin 3 ELISA Kit

Product Gene Name

CST3 elisa kit

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Detection Range

62.5ng/ml-2000ng/ml

Sensitivity

10ng/ml

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Molecular Weight

16,388 Da

OMIM

123855

3D Structure

ModBase 3D Structure for P01037

Other Notes

Small volumes of CST3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CST3 purchase

MBS087116 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cystatin 3 (CST3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CST3. The ELISA analytical biochemical technique of the MBS087116 kit is based on CST3 antibody-CST3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CST3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CST3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CST3. It may not necessarily be applicable to this product.

NCBI GI #

337752

NCBI GeneID

1469

NCBI Accession #

AAA60299.1

UniProt Primary Accession #

P01037

UniProt Secondary Accession #

Q96LE6; Q9UCQ6

UniProt Related Accession #

P01037

NCBI Official Full Name

cystatin

NCBI Official Synonym Full Names

cystatin SN

NCBI Official Symbol

CST1

UniProt Protein Name

Cystatin-SN

UniProt Synonym Protein Names

Cystain-SA-I; Cystatin-1; Salivary cystatin-SA-1

Protein Family

Cystatin

UniProt Gene Name

CST1

UniProt Entry Name

CYTN_HUMAN

NCBI Protein Information

cystatin-SN; cystatin 1; cystatin-1; cystain-SA-I; cystatin SA-I; salivary cystatin-SA-1; cysteine proteinase inhibitor, type 2 family

NCBI Summary for CST3

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a cysteine proteinase inhibitor found in saliva, tears, urine, and seminal fluid. [provided by RefSeq, Jul 2008]

UniProt Comments for CST3

CST1: Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well. Belongs to the cystatin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 20p11.21

Cellular Component: extracellular space

Molecular Function: cysteine protease inhibitor activity

Biological Process: detection of chemical stimulus involved in sensory perception of bitter taste

Research Articles on CST3

1. CST1 may contribute to inactivation of protease allergens and help re-establish homeostasis of the nasal membranes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CST3 elisa kit

Products by Pathway	Pathway Diagram
Salivary Secretion Pathway antibodies	Salivary Secretion Pathway Diagram
Salivary Secretion Pathway antibodies	Salivary Secretion Pathway Diagram

Diseases associated with CST3 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>7 publications with CST3 and Neoplasms
Necrosis Antibodies	>2 publications with CST3 and Necrosis
Adenocarcinoma Antibodies	>1 publications with CST3 and Adenocarcinoma
Breast Neoplasms Antibodies	>1 publications with CST3 and Breast Neoplasms
Neoplasms, Experimental Antibodies	>1 publications with CST3 and Neoplasms, Experimental
Hyperplasia Antibodies	>1 publications with CST3 and Hyperplasia
Skin Diseases Antibodies	>1 publications with CST3 and Skin Diseases
Lung Diseases Antibodies	>1 publications with CST3 and Lung Diseases
Rhinitis, Allergic, Seasonal Antibodies	>1 publications with CST3 and Rhinitis, Allergic, Seasonal
Inflammation Antibodies	>1 publications with CST3 and Inflammation

Organs/Tissues associated with CST3 elisa kit

Organ/Tissue Name	Pubmed Publications
Salivary Gland Antibodies	>8 publications with CST3 and Salivary Gland
Prostate Antibodies	>2 publications with CST3 and Prostate
Muscle Antibodies	>1 publications with CST3 and Muscle
Adrenal Gland Antibodies	>1 publications with CST3 and Adrenal Gland