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Potassium Channel Toxin Kappa-Ktx 2.2 Opisthacanthus Madagascariensis Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1015003

MBS1015003 is a recombinant protein targeting Potassium channel toxin kappa-KTx 2.2. Also known as Recombinant Opisthacanthus madagascariensis Potassium channel toxin kappa-KTx 2.2. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$625 / 0.05 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Potassium channel toxin kappa-KTx 2.2, Recombinant Protein
Full Product Name
Recombinant Opisthacanthus madagascariensis Potassium channel toxin kappa-KTx 2.2
Product Synonym Names
Recombinant Potassium channel toxin kappa-KTx 2.2; Potassium channel toxin kappa-KTx 2.2; Toxin OmTx2 Cleaved into the following 2 chains: 1. Potassium channel toxin kappa-KTx 2.1; Toxin OmTx1 Potassium channel toxin kappa-KTx 2.4; Toxin OmTx4
Sequence
DPCYEVCLQQ HGNVKECEEA CKHPVEY
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
3,152 Da
Sequence Positions
1-27aa; Cytoplasmic domain
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P0C1Z3
Species
Opisthacanthus madagascariensis (Scorpion)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Potassium channel toxin kappa-KTx 2.2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Potassium channel toxin kappa-KTx 2.2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
NCBI Official Full Name
Potassium channel toxin kappa-KTx 2.2
UniProt Protein Name
Potassium channel toxin kappa-KTx 2.2
UniProt Synonym Protein Names
Toxin OmTx2Cleaved into the following 2 chains:Potassium channel toxin kappa-KTx 2.1; Alternative name(s):; Toxin OmTx1Potassium channel toxin kappa-KTx 2.4; Alternative name(s):; Toxin OmTx4
UniProt Entry Name
KKX21_OPIMA

UniProt Comments for Potassium channel toxin kappa-KTx 2.2

Function: OmTx1 decreases the amplitude of the potassium current of the rat channels Kv1.1/KCNA1 by 17% and Kv1.2/KCNA2 by 12% as well as human Kv1.3/KCNA3 by 24%. Ref.1OmTx2 decreases the amplitude of the potassium current of the rat channels Kv1.1/KCNA1 by 8% and Kv1.2/KCNA2 by 10% as well as human Kv1.3/KCNA3 by 36%. Also alters glucose-induced insulin release from pancreatic islets. Ref.1

Subcellular location: Secreted.

Tissue specificity: Expressed by the venom gland.

Domain: Has the structural arrangement of two alpha-helices stabilized by two disulfide bonds (CSalpha/alpha).

Sequence similarities: Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor kappa-KTx family. Kappa-KTx 2 subfamily.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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