Urocortin 2 (UCN2) ELISA Kit for Rabbit

Name: Rabbit UCN2 ELISA Kit; Urocortin 2; MyBioSource
Brand: MyBioSource
SKU: MBS101558
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS101558

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of UCN2 (hereafter termed "analyte") in undiluted original Rabbit body fluids, tissue… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Urocortin 2 (UCN2), ELISA Kit

Full Product Name

Rabbit Urocortin 2 ELISA Kit

Product Gene Name

UCN2 elisa kit

Species Reactivity

Rabbit

Assay Type

Sandwich

Samples

Undiluted original Rabbit body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

Detection Range

0.625 ng/ml - 20 ng/ml.

Sensitivity

0.1 ng/ml.

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

13,458 Da

OMIM

600945

3D Structure

ModBase 3D Structure for P55089

Other Notes

Small volumes of UCN2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UCN2 purchase

MBS101558 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Urocortin 2 (UCN2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing UCN2. The ELISA analytical biochemical technique of the MBS101558 kit is based on UCN2 antibody-UCN2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect UCN2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, UCN2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for UCN2. It may not necessarily be applicable to this product.

NCBI GI #

4507803

NCBI GeneID

7349

NCBI Accession #

NP_003344.1

UniProt Primary Accession #

P55089

UniProt Secondary Accession #

Q6FG64

UniProt Related Accession #

P55089

GenBank Nucleotide #

NM_003353.2

NCBI Official Full Name

urocortin preproprotein

NCBI Official Synonym Full Names

urocortin

NCBI Official Symbol

UCN

NCBI Official Synonym Symbols

UI; UROC

UniProt Protein Name

Urocortin

Protein Family

Urocortin

UniProt Gene Name

UCN

UniProt Entry Name

UCN1_HUMAN

NCBI Protein Information

urocortin; prepro-urocortin; urocortin, preproprotein

NCBI Summary for UCN2

This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq, Jul 2008]

UniProt Comments for UCN2

UCN: Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH). Binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta. Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 2p23.3

Cellular Component: dendrite; extracellular region; perikaryon; nerve terminal

Molecular Function: corticotropin-releasing hormone receptor 1 binding; histone deacetylase inhibitor activity; neuropeptide hormone activity; protein binding; corticotropin-releasing hormone receptor 2 binding

Biological Process: regulation of synaptic transmission, glutamatergic; positive regulation of translation; negative regulation of hormone secretion; response to glucocorticoid stimulus; positive regulation of collagen biosynthetic process; drinking behavior; response to pain; negative regulation of cell size; female pregnancy; positive regulation of vasodilation; pancreatic juice secretion; negative regulation of appetite; response to estradiol stimulus; positive regulation of adrenocorticotropic hormone secretion; sensory perception of sound; neuropeptide signaling pathway; positive regulation of cAMP biosynthetic process; negative regulation of blood pressure; inflammatory response; neurite development; associative learning; negative regulation of histone deacetylation; activation of protein kinase A; positive regulation of interleukin-6 production; social behavior; positive regulation of cell growth; positive regulation of peptidyl-serine phosphorylation; positive regulation of vascular permeability; G-protein coupled receptor protein signaling pathway; aerobic respiration; response to oxidative stress; positive regulation of DNA replication; negative regulation of apoptosis

Research Articles on UCN2

1. all neonates expressed UCN1 in the Edinger-Westphal nucleus independent of the degree of neuropathological injury.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with UCN2 elisa kit

Reference Product	PubMed Publications
CRHR2 elisa kit	>22 publications with UCN2 and CRHR2
FOS elisa kit	>21 publications with UCN2 and FOS
CRHR1 elisa kit	>17 publications with UCN2 and CRHR1
CRHBP elisa kit	>7 publications with UCN2 and CRHBP
IL6 elisa kit	>2 publications with UCN2 and IL6
PLA2G6 elisa kit	>1 publications with UCN2 and PLA2G6

Diseases associated with UCN2 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>237 publications with UCN2 and Neoplasms
Cardiovascular Diseases Antibodies	>68 publications with UCN2 and Cardiovascular Diseases
Disease Models, Animal Antibodies	>37 publications with UCN2 and Disease Models, Animal
Breast Neoplasms Antibodies	>35 publications with UCN2 and Breast Neoplasms
Heart Diseases Antibodies	>32 publications with UCN2 and Heart Diseases
Inflammation Antibodies	>31 publications with UCN2 and Inflammation
Mitochondrial Diseases Antibodies	>28 publications with UCN2 and Mitochondrial Diseases
Necrosis Antibodies	>22 publications with UCN2 and Necrosis
Adenocarcinoma Antibodies	>22 publications with UCN2 and Adenocarcinoma
Neoplasms, Experimental Antibodies	>19 publications with UCN2 and Neoplasms, Experimental

Organs/Tissues associated with UCN2 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>200 publications with UCN2 and Brain
Lung Antibodies	>37 publications with UCN2 and Lung
Bone Antibodies	>24 publications with UCN2 and Bone
Adrenal Gland Antibodies	>22 publications with UCN2 and Adrenal Gland
Kidney Antibodies	>21 publications with UCN2 and Kidney
Skin Antibodies	>20 publications with UCN2 and Skin
Intestine Antibodies	>15 publications with UCN2 and Intestine
Ovary Antibodies	>14 publications with UCN2 and Ovary
Uterus Antibodies	>13 publications with UCN2 and Uterus
Embryonic Tissue Antibodies	>10 publications with UCN2 and Embryonic Tissue