Bovine TRPC1 Recombinant Protein – Cat# MBS1017508

Short Transient Receptor Potential Channel 1 (TRPC1) Bovine Recombinant Protein

Name: TRPC1 Recombinant Protein; Bovine; MyBioSource
Brand: MyBioSource
SKU: MBS1017508
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1017508

MBS1017508 is a recombinant protein targeting TRPC1. Also known as Recombinant Bovine Short transient receptor potential channel 1 (TRPC1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Short transient receptor potential channel 1 (TRPC1), Recombinant Protein

Full Product Name

Recombinant Bovine Short transient receptor potential channel 1 (TRPC1)

Product Gene Name

TRPC1 recombinant protein

Product Synonym Gene Name

TRPC1; TRP1

Product Synonym Names

Recombinant Short transient receptor potential channel 1 (TRPC1); Short transient receptor potential channel 1; TrpC1; Transient receptor protein 1; TRP-1

Sequence

MMAALYPSTD LSGASSSSLP SSPSSSSPNE VMALKDVREV KEENTLNEKL FLLACDKGDY YMVKEILEEN SSGDLNINCV DVLGRNAVTI TIENENLDIL QLLLDYGCQS ADALLVAIDS EVVGAVDILL NHRPKRSSRP TIVKLMERIQ NPEYSTTMDV APVILAAHRN NYEILTMLLK QDVSLPKPHA VGCECTLCSA KNKKDSLRHS RFRLDIYRCL ASPALIMLTE EDPILGAFEL SADLKELSLV EVEFRNDYEE LARQCKMFAK DLLAQARNSR ELEVILNHTS NDEPLDKRGL LEERMNLSRL KLAIKYNQKE FVSQSNCQQF LNTVWFGQMS GYRRKPTCKK IMTVLTVGIF WPVLSLCYLI APKSQFGRII HTPFMKFIIH GASYFTFLLL LNLYSLVYHE DKKNTMGPAL ERIDYLLILW IIGMIWSDIK RLWYEGLEDF LEESRNQLSF VMNSLYLATF ALKEEAHNKF HDFADRKDWD AFHPTLVAEG LFAFANVLSY LRLFFYVYTS SILGPLQISM GRMLQDFGKF LGMFLLVLFS FTIGLTQLYD KGYTPKEQKD CVGIFCEQQS NDTFHSFIGT CFALFWYIFS LAHVAILCTR FSYGEELQSF VGAFIVGTYN VVVVIVLTKL LVAMLHKSFQ LIANHEDKEW KFARAKLWLS YFDDKCTLPP PFNIIPSPKT ICYMISSLSK WICSHTSKGK VKRQNSLKEW RHLNEKRDEN YQKVMCCLVR RYLTSMRQKM QSTDQATVEN LNELRQDLSK FRNEIRDLLG FRTSKYAMFY PRN

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

91,339 Da

Sequence Positions

1-793

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: 1; AC_000158.1 (127257290..127318223, complement). Location: chromosome: 1

3D Structure

ModBase 3D Structure for O18784

Species

Bos taurus (Bovine)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of TRPC1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TRPC1. It may not necessarily be applicable to this product.

NCBI GI #

27806169

NCBI GeneID

282100

NCBI Accession #

NP_776901.1

UniProt Primary Accession #

O18784

UniProt Secondary Accession #

O18785

UniProt Related Accession #

O18784

GenBank Nucleotide #

NM_174476.2

NCBI Official Full Name

short transient receptor potential channel 1

NCBI Official Symbol

TRPC1

UniProt Protein Name

Short transient receptor potential channel 1

UniProt Synonym Protein Names

Transient receptor protein 1

Protein Family

Indole-3-glycerol phosphate synthase

UniProt Gene Name

TRPC1

UniProt Synonym Gene Names

TRP1; TrpC1; TRP-1

UniProt Entry Name

TRPC1_BOVIN

NCBI Protein Information

short transient receptor potential channel 1; TRP-1; transient receptor protein 1

UniProt Comments for TRPC1

Function: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

Subunit structure: Homotetramer and heterotetramer with TRPC4 and/or TRPC5

By similarity. Interacts with TRPC3, TRPC4 and TRPC5

By similarity. Interacts with ITPR3

By similarity. Interacts with MX1 and RNF24

By similarity. Interacts with FKBP4

By similarity. Interacts with TRPC4AP

By similarity.

Subcellular location: Membrane; Multi-pass membrane protein

Probable.

Sequence similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily. [View classification]Contains 4 ANK repeats.

Research Articles on TRPC1

1. the link between HG-induced changes in TRPC1 expression, enhanced Ca(2+) entry, and endothelial dysfunction require further study

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TRPC1 recombinant protein

Products by Pathway	Pathway Diagram
Glutamatergic Synapse Pathway antibodies	Glutamatergic Synapse Pathway Diagram
Glutamatergic Synapse Pathway antibodies	Glutamatergic Synapse Pathway Diagram
Pancreatic Secretion Pathway antibodies	Pancreatic Secretion Pathway Diagram
Pancreatic Secretion Pathway antibodies	Pancreatic Secretion Pathway Diagram
Serotonergic Synapse Pathway antibodies	Serotonergic Synapse Pathway Diagram

Diseases associated with TRPC1 recombinant protein

Disease Name	Pubmed Publications
Neoplasms Antibodies	>27 publications with TRPC1 and Neoplasms
Hypertension Antibodies	>27 publications with TRPC1 and Hypertension
Heart Diseases Antibodies	>20 publications with TRPC1 and Heart Diseases
Necrosis Antibodies	>14 publications with TRPC1 and Necrosis
Brain Diseases Antibodies	>9 publications with TRPC1 and Brain Diseases
Muscular Diseases Antibodies	>9 publications with TRPC1 and Muscular Diseases
Cardiomegaly Antibodies	>9 publications with TRPC1 and Cardiomegaly
Inflammation Antibodies	>8 publications with TRPC1 and Inflammation
Pain Antibodies	>7 publications with TRPC1 and Pain
Myocardial Ischemia Antibodies	>7 publications with TRPC1 and Myocardial Ischemia

Organs/Tissues associated with TRPC1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>66 publications with TRPC1 and Brain