Sheep Pulmonary Adenomatosis Virus env Recombinant Protein – Cat# MBS1018265

Envelope Glycoprotein (env) Sheep Pulmonary Adenomatosis Virus Recombinant Protein

Name: env Recombinant Protein; Sheep Pulmonary Adenomatosis Virus; MyBioSource
Brand: MyBioSource
SKU: MBS1018265
Price: 1435 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1018265

MBS1018265 is a recombinant protein targeting env. Also known as Recombinant Sheep pulmonary adenomatosis virus Envelope glycoprotein (env), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1435 / 0.5 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Envelope glycoprotein (env), Recombinant Protein

Full Product Name

Recombinant Sheep pulmonary adenomatosis virus Envelope glycoprotein (env), partial

Product Gene Name

env recombinant protein

Sequence

AYIPDP PMIQSLGWDR EIVPVYVNDT SLLGGKSDIH ISPQQANISF YGLTTQYPMC FSYQSQHPHC IQVSADISYP RVTISGIDEK TGKKSYGNGT GPLDIPFCDK HLSIGIGIDT PWTLCRARVA SVYNINNANA TFLWDWAPGG TPDFPEYRGQ HPPIFSVNTA PIYQTELWKL LAAFGHGNSL YLQPNISGTK YGDVGVTGFL YPRACVPYPF MLIQGHMEIT LSLNIYHLNC SNCILTNCIR GVAKGEQVII VKQPAFVMLP VEIAEAWYDE TALELLQRIN TALSRPKR

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

69,343 Da

Sequence Positions

85-378

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for P31621

Species

Sheep pulmonary adenomatosis virus (Jaagsiekte sheep retrovirus) (JSRV)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of env recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for env. It may not necessarily be applicable to this product.

NCBI GI #

9626919

NCBI GeneID

1490021

NCBI Accession #

NP_041188.1

UniProt Primary Accession #

P31621

UniProt Related Accession #

VCMVJA

GenBank Nucleotide #

NC_001494.1

NCBI Official Full Name

envelope protein

NCBI Official Symbol

env

UniProt Protein Name

Envelope glycoprotein

UniProt Synonym Protein Names

Env polyprotein

Protein Family

Envelope glycoprotein

UniProt Gene Name

env

UniProt Synonym Gene Names

SU; gp52; TM; gp36

NCBI Protein Information

envelope protein

UniProt Comments for env

The envelope proteins induce cell transformation leading to ovine pulmonary adenocarcinoma (OPA), a contagious lung cancer of sheep and goat. They bind to the HYAL2 receptor for cell entry. Env proteins probably do not act as oncogenes by themselves, but may rather liberate an oncogenic factor that would normally be negatively regulated. One mechanism of transformation seems to involve activation of the phosphoinositide-3-OH kinase (PI3K)/Akt pathway but does not involve the virus receptor HYAL2, and the other seems to involve Env binding to HYAL2, HYAL2 degradation, and activation of the MST1R receptor tyrosine kinase, which is normally suppressed by HYAL2.

Research Articles on env

1. BST2B acts differently from BST2A by leading to a reduction in Jaagsiekte sheep retrovirus Env incorporation into viral particles, which ultimately results in the release of virions that are less infectious.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.