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Neuropeptide Y Receptor Type 5 (NPY5R) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1022889

MBS1022889 is a recombinant protein targeting Npy5r. Also known as Recombinant Mouse Neuropeptide Y receptor type 5 (Npy5r). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Neuropeptide Y receptor type 5 (Npy5r), Recombinant Protein
Full Product Name
Recombinant Mouse Neuropeptide Y receptor type 5 (Npy5r)
Product Gene Name
Npy5r recombinant protein
Product Synonym Gene Name
Npy5r; Npy5
Product Synonym Names
Recombinant Neuropeptide Y receptor type 5 (Npy5r); Neuropeptide Y receptor type 5; NPY5-R; NPY-Y5 receptor; NPYY5-R; Y5 receptor
Sequence
MEVKLEEHFN KTFVTENNTA ASQNTASPAW EDYRGTENNT SAARNTAFPV WEDYRGSVDD LQYFLIGLYT FVSLLGFMGN LLILMAVMKK RNQKTTVNFL IGNLAFSDIL VVLFCSPFTL TSVLLDQWMF GKAMCHIMPF LQCVSVLVST LILISIAIVR YHMIKHPISN NLTANHGYFL IATVWTLGFA ICSPLPVFHS LVELKETFGS ALLSSKYLCV ESWPSDSYRI AFTISLLLVQ YILPLVCLTV SHTSVCRSIS CGLSHKENRL EENEMINLTL HPSKKSRDQA KPPSTQKWSY SFIRKHRRRY SKKTACVLPA PAGPSQEKHL TVPENPGSVR SQLSPSSKVI PGVPICFEVK PEESSDAQEM RVKRSLTRIK KRSRSVFYRL TILILVFAVS WMPLHVFHVV TDFNDNLISN RHFKLVYCIC HLLGMMSCCL NPILYGFLNN GIKADLRALI HCLHMS
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
52,785 Da
Sequence Positions
1-466
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: 8; NC_000074.6 (66679965..66688094, complement). Location: 8 B3-C2; 8 33.15 cM
3D Structure
ModBase 3D Structure for O70342
Species
Mus musculus (Mouse)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Npy5r recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Npy5r. It may not necessarily be applicable to this product.

NCBI GI #
157057095
NCBI GeneID
18168
NCBI Accession #
NP_057917.2
UniProt Primary Accession #
O70342
UniProt Secondary Accession #
O35380; Q9JMK1
UniProt Related Accession #
O70342
GenBank Nucleotide #
NM_016708.3
NCBI Official Full Name
neuropeptide Y receptor type 5
NCBI Official Synonym Full Names
neuropeptide Y receptor Y5
NCBI Official Symbol
Npy5r
NCBI Official Synonym Symbols
Y5R; NPY5-R; NPYY5-R
UniProt Protein Name
Neuropeptide Y receptor type 5
UniProt Synonym Protein Names
NPY-Y5 receptor
Protein Family
Neuropeptide Y receptor
UniProt Gene Name
Npy5r
UniProt Synonym Gene Names
Npy5; NPY5-R; NPYY5-R; Y5 receptor
UniProt Entry Name
NPY5R_MOUSE
NCBI Protein Information
neuropeptide Y receptor type 5; Y5 receptor; NPY-Y5 receptor

UniProt Comments for Npy5r

NPY5R: Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral

Cellular Component: neuron projection; membrane; cytoplasm; integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; peptide YY receptor activity; signal transducer activity; pancreatic polypeptide receptor activity; neuropeptide Y receptor activity

Biological Process: generation of ovulation cycle rhythm; G-protein coupled receptor protein signaling pathway; synaptic transmission; negative regulation of glutamate secretion; positive regulation of acute inflammatory response; neuropeptide signaling pathway; eating behavior; positive regulation of smooth muscle cell proliferation; signal transduction; negative regulation of synaptic transmission, GABAergic; negative regulation of apoptosis
Show more

Research Articles on Npy5r

1. These studies demonstrate the pivotal, combined role of both Y1 and Y5 receptors in the mediation of food intake.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Npy5r recombinant protein

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Peptide GPCRs Pathway antibodies  Peptide GPCRs Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Diseases associated with Npy5r recombinant protein

 Disease Name  Pubmed Publications
 Obesity Antibodies  >8 publications with Npy5r and Obesity
 Nervous System Diseases Antibodies  >2 publications with Npy5r and Nervous System Diseases
 Memory Disorders Antibodies  >1 publications with Npy5r and Memory Disorders
 Dyslipidemias Antibodies  >1 publications with Npy5r and Dyslipidemias
 Seizures Antibodies  >1 publications with Npy5r and Seizures
 Cardiomegaly Antibodies  >1 publications with Npy5r and Cardiomegaly
 Liver Diseases Antibodies  >1 publications with Npy5r and Liver Diseases
 Disease Models, Animal Antibodies  >1 publications with Npy5r and Disease Models, Animal
 Hypertrophy Antibodies  >1 publications with Npy5r and Hypertrophy
 Hypertension Antibodies  >1 publications with Npy5r and Hypertension

Organs/Tissues associated with Npy5r recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with Npy5r and Brain
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