Mesocricetus Auratus HSD3B3 Recombinant Protein – Cat# MBS1026074

3 Beta-Hydroxysteroid Dehydrogenase Type 3 (HSD3B3) Mesocricetus Auratus Recombinant Protein

Name: HSD3B3 Recombinant Protein; Mesocricetus Auratus; MyBioSource
Brand: MyBioSource
SKU: MBS1026074
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1026074

MBS1026074 is a recombinant protein targeting HSD3B3. Also known as Recombinant Mesocricetus auratus 3 beta-hydroxysteroid dehydrogenase type 3 (HSD3B3). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

3 beta-hydroxysteroid dehydrogenase type 3 (HSD3B3), Recombinant Protein

Full Product Name

Recombinant Mesocricetus auratus 3 beta-hydroxysteroid dehydrogenase type 3 (HSD3B3)

Product Gene Name

HSD3B3 recombinant protein

Product Synonym Gene Name

HSD3B3

Product Synonym Names

Recombinant 3 beta-hydroxysteroid dehydrogenase type 3 (HSD3B3); 3 beta-hydroxysteroid dehydrogenase type 3; 3 beta-hydroxysteroid dehydrogenase type III; 3-beta-HSD III 3-beta-hydroxy-5-ene steroid dehydrogenase NADP-dependent 3-beta-hydroxy-Delta(5)-ste

Sequence

PAWSCLVTGA GGFLGQRIIR MLAQEKELQE VRTLFRSFTP KHREELSKLQ TKTKVTVLEG DILDAQCLRR ACQGISVVIH TAAAIDVFGA IPRQTVIDIN LKGTQHLLDA CIGARVPVFI YSSSVAVAGP NSYKVIIQNG SEEENHESTW SDPYAYSKKM AEKAVLAANG STLKDGGTLH TCALRLPFIY GEKSKFISDT MDRALKNNGL INGFSRFSVI SSVYVNNAAW AHVLAARGLQ DPKKSPNIQG QFYYISDDTP HQSYDDLCYT LSKDWGLRPD SSWKPPVALL YWFGFLLETV SFLLRPVYNY QPPFNRHLVT LLNSVFTFSY KKAQRDLGYE PLVSWEEARE KTSEWIGSLV EQHKGTLNIK AQ

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

41,806 Da

Sequence Positions

2-373

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for O35296

Species

Mesocricetus auratus (Golden hamster)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of HSD3B3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HSD3B3. It may not necessarily be applicable to this product.

NCBI GI #

3334104

NCBI Accession #

O35296.3

UniProt Primary Accession #

O35296

NCBI Official Full Name

3 beta-hydroxysteroid dehydrogenase type 3

UniProt Protein Name

3 beta-hydroxysteroid dehydrogenase type 3

UniProt Synonym Protein Names

3 beta-hydroxysteroid dehydrogenase type III; 3-beta-HSD III; 3-beta-hydroxy-5-ene steroid dehydrogenase; NADP-dependent 3-beta-hydroxy-Delta(5)-steroid dehydrogenase (EC:1.1.1.-); Progesterone reductase

Protein Family

3 beta-hydroxysteroid dehydrogenase

UniProt Gene Name

HSD3B3

UniProt Synonym Gene Names

3-beta-HSD III

UniProt Entry Name

3BHS3_MESAU

UniProt Comments for HSD3B3

Function: 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. This isoform possesses no isomerase activity but functions as a 3-ketosteroid reductase with a preference for NADP.

Catalytic activity: 3-beta-hydroxy-Delta(5)-steroid + NADP+ = 3-oxo-Delta(5)-steroid + NADPH.

Pathway: Lipid metabolism; steroid biosynthesis.

Subcellular location: Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.

Tissue specificity: High levels in adrenal, kidney and male liver. Low levels in female liver.

Sequence similarities: Belongs to the 3-beta-HSD family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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