Puumala Virus GP Recombinant Protein – Cat# MBS1027459

Envelope Glycoprotein (GP) Puumala Virus Recombinant Protein

Name: GP Recombinant Protein; Envelope Glycoprotein; Puumala Virus; MyBioSource
Brand: MyBioSource
SKU: MBS1027459
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1027459

MBS1027459 is a recombinant protein targeting GP. Also known as Recombinant Puumala virus Envelope glycoprotein (GP). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Envelope glycoprotein (GP), Recombinant Protein

Full Product Name

Recombinant Puumala virus Envelope glycoprotein (GP)

Product Gene Name

GP recombinant protein

Product Synonym Gene Name

Product Synonym Names

Recombinant Envelope glycoprotein (GP); Envelope glycoprotein; GP; M polyprotein Cleaved into the following 2 chains: 1. Glycoprotein G1 2. Glycoprotein G2

Sequence

ETQNLNAGWT DTAHGSGIIP MKTDLELDFS LPSSASYTYR RQLQNPANEQ EKIPFHLQLS KQVIHAEIQH LGHWMDATFN LKTAFHCYGS CEKYAYPWQT AGCFIEKDYE YETGWGCNPP DCPGVGTGCT ACGVYLDKLK SVGKVFKIVS LRYTRKVCIQ LGTEQTCKTV DSNDCLITTS VKVCLIGTIS KFQPSDTLLF LGPLQQGGLI FKQWCTTTCQ FGDPGDIMST PTGMKCPELN GSFRKKCAFA TTPVCQFDGN TISGYKRMIA TKDSFQSFNV TEPHISTSAL EWIDPDSSLR DHINVIVSRD LSFQDLSETP CQIDLATASI DGAWGSGVGF NLVCTVSLTE CSAFLTSIKA CDAAMCYGST TANLVRGQNT IHIVGKGGHS GSKFMCCHDT KCSSTGLVAA APHLDRVTGY NQADSDKIFD DGAPECGMSC WFKKSGEWIL GVLNGNWMVV AVLVVLLILS ILLFTLCCPR RPSYRKEHKP

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

126,574 Da

Sequence Positions

659-1148

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for P41266

Species

Puumala virus (strain P360)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GP. It may not necessarily be applicable to this product.

NCBI GI #

731116

NCBI Accession #

P41266.1

UniProt Primary Accession #

P41266

NCBI Official Full Name

Envelope glycoprotein

UniProt Protein Name

Envelope glycoprotein

UniProt Synonym Protein Names

M polyprotein

Protein Family

Envelopment polyprotein

UniProt Gene Name

UniProt Synonym Gene Names

UniProt Entry Name

GP_PUUMP

UniProt Comments for GP

Function: Glycoprotein G1 and glycoprotein G2 interact with each other and are present at the surface of the virion. They are able to attach the virion to a cell receptor and to promote fusion of membranes after endocytosis of the virion. G1 contains an ITAM motif which is likely to dysregulate normal immune and endothelial cell responses and contribute to virus pathogenesis

By similarity.

Subunit structure: G1 and G2 interacts with each other

By similarity.

Subcellular location: Glycoprotein G1: Virion membrane; Single-pass type I membrane protein

Potential. Host Golgi apparatus membrane; Single-pass type I membrane protein

Potential. Host endoplasmic reticulum membrane; Single-pass type I membrane protein

Potential. Note: Interaction between G1 and G2 is essential for proper targeting of G1 to the Golgi complex, where virion budding occurs

By similarity.Glycoprotein G2: Virion membrane; Single-pass type I membrane protein

Potential. Host Golgi apparatus membrane; Single-pass type I membrane protein

Potential.

Post-translational modification: Specific enzymatic cleavages in vivo yield mature proteins including glycoprotein G1 and glycoprotein G2.

Sequence similarities: Belongs to the hantavirus envelope glycoprotein family.Contains 1 ITAM domain.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GP recombinant protein

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