Mouse ARX Recombinant Protein – Cat# MBS1034191

Homeobox Protein ARX (ARX) Mouse Recombinant Protein

Name: ARX Recombinant Protein; Homeobox Protein ARX; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS1034191
Price: 1360 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1034191

This gene is a homeobox-containing gene expressed during development. The expressed protein contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain. It is a member of the group-II aristaless-related protein… More details

$1360 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Homeobox protein ARX (Arx), Recombinant Protein

Full Product Name

Recombinant Mouse Homeobox protein ARX (Arx)

Product Gene Name

Arx recombinant protein

Sequence

MSNQYQEEGC SERPECKSKS PTLLSSYCID SILGRRSPCK MRLLGAAQSL PAPLASRADQ EKAMQGSPKS SSAPFEAELH LPPKLRRLYG PGGGRLLQGA AAAAAAAAAA AAAATATGTA GPRGEVPPPP PPAARPGERQ DSAGAVAAAA AAAAWDTLKI SQAPQVSISR SKSYRENGAP FVPPPPALDE LSGPGGVAHP EERLSAASGP GSAPAAGGGT GAEDDEEELL EDEEDEEEEE ELLEDDDEEL LEDDARALLK EPRRCSVATT GTVAAAAAAA AAAVATEGGE LSPKEELLLH PEDAEGKDGE DSVCLSAGSD SEEGLLKRKQ RRYRTTFTSY QLEELERAFQ KTHYPDVFTR EELAMRLDLT EARVQVWFQN RRAKWRKREK AGAQTHPPGL PFPGPLSATH PLSPYLDASP FPPHHPALDS AWTAAAAAAA AAFPSLPPPP GSASLPPSGA PLGLSTFLGA AVFRHPAFIS PAFGRLFSTM APLTSASTAA ALLRQPTPAV EGAVASGALA DPATAAADRR ASSIAALRLK AKEHAAQLTQ LNILPGTSTG KEVC

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

58,490 Da

Sequence Positions

1-564, Full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for O35085

Species

Mouse

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Arx recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Arx purchase

MBS1034191 is a recombinant protein targeting Arx. Also known as Recombinant Mouse Homeobox protein ARX (Arx). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Arx. It may not necessarily be applicable to this product.

NCBI GI #

806776662

NCBI GeneID

11878

NCBI Accession #

NP_001292869.1

UniProt Primary Accession #

O35085

UniProt Secondary Accession #

Q9QYT4; A2A4G9

UniProt Related Accession #

O35085

GenBank Nucleotide #

NM_001305940.1

NCBI Official Full Name

homeobox protein ARX

NCBI Official Synonym Full Names

aristaless related homeobox

NCBI Official Symbol

Arx

NCBI Official Synonym Symbols

Arx1

UniProt Protein Name

Homeobox protein ARX

UniProt Synonym Protein Names

Aristaless-related homeobox

Protein Family

Aristaless-related homeobox protein

UniProt Gene Name

Arx

NCBI Protein Information

homeobox protein ARX

NCBI Summary for Arx

This gene encodes a transcription factor that plays an important role in the development of forebrain. Male mice lacking this gene have smaller brains, olfactory bulbs and testes, and die within half a day after birth. Mice lacking this gene specifically in ganglionic eminence-derived neurons, including cortical interneurons, develop seizures. Mutations in this gene have been demonstrated to cause mouse phenotypes resembling human X-linked lissencephaly and cognitive disability with epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

UniProt Comments for Arx

Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate ().

Research Articles on Arx

1. Study provides further support that the role of Arx in interneuron development is to direct appropriate migration of ventral neuronal precursors into the dorsal cortex and that the loss of Arx results in a failure of interneurons to reach the cortex and thus a deficiency in interneurons.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Arx recombinant protein

Reference Product	PubMed Publications
Tuba1a recombinant protein	>15 publications with Arx and Tuba1a
Son recombinant protein	>2 publications with Arx and Son
Mef2c recombinant protein	>2 publications with Arx and Mef2c

Diseases associated with Arx recombinant protein

Disease Name	Pubmed Publications
Mental Retardation, X-Linked, With Or Without Seizures, Arx-Related Antibodies	>88 publications with Arx and Mental Retardation, X-Linked, With Or Without Seizures, Arx-Related
Neurobehavioral Manifestations Antibodies	>81 publications with Arx and Neurobehavioral Manifestations
Abnormalities, Multiple Antibodies	>25 publications with Arx and Abnormalities, Multiple
Disease Models, Animal Antibodies	>20 publications with Arx and Disease Models, Animal
Neurodegenerative Diseases Antibodies	>9 publications with Arx and Neurodegenerative Diseases
Lissencephaly, X-Linked, 2 Antibodies	>8 publications with Arx and Lissencephaly, X-Linked, 2
Fibrosis Antibodies	>5 publications with Arx and Fibrosis
Learning Disorders Antibodies	>5 publications with Arx and Learning Disorders
Necrosis Antibodies	>3 publications with Arx and Necrosis
Kidney Diseases Antibodies	>3 publications with Arx and Kidney Diseases

Organs/Tissues associated with Arx recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>154 publications with Arx and Brain
Heart Antibodies	>26 publications with Arx and Heart
Embryonic Tissue Antibodies	>23 publications with Arx and Embryonic Tissue
Testis Antibodies	>8 publications with Arx and Testis