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Syntaxin-6 (STX6) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1035024

MBS1035024 is a recombinant protein targeting STX6. Also known as Recombinant Human Syntaxin-6. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. Involved in intracellular vesicle trafficking. More details

$335 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Syntaxin-6 (STX6), Recombinant Protein
Full Product Name
Recombinant Human Syntaxin-6
Product Gene Name
STX6 recombinant protein
Sequence
DPFFVVKGEV QKAVNTAQGL FQRWTELLQD PSTATREEID WTTNELRNNL RSIEWDLEDL DETISIVEAN PRKFNLDATE LSIRKAFITS TRQVVRDMKD QMSTSSVQAL AERKNRQALL GDSGSQNWST GTTDKYGRLD RELQRANSHF IEEQQAQQQL IVEQQDEQLE LVSGSIGVLK NMSQRIGGEL EEQAVMLEDF SHELESTQSR LDNVMKKLAK VSHMTSDRRQ
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Molecular Weight
53.4 kDa
Sequence Positions
5-234aa; Partial
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
603944
3D Structure
ModBase 3D Structure for O43752

Product Categories/Family for STX6 recombinant protein

Transport
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

SDS-PAGE of STX6 recombinant protein

Human STX6 Recombinant Protein – Cat# MBS1035024

Product References and Citations for STX6 recombinant protein

Co-expression of several human syntaxin genes in neutrophils and differentiating HL-60 cells variant isoforms and detection of syntaxin 1.Martin-Martin B., Nabokina S.M., Lazo P.A., Mollinedo F.J. Leukoc. Biol. 65:397-406(1999)

Other Notes

Small volumes of STX6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for STX6. It may not necessarily be applicable to this product.

NCBI GI #
555290010
NCBI GeneID
10228
NCBI Accession #
NP_001273139.1
UniProt Primary Accession #
O43752
UniProt Secondary Accession #
Q5VY08; Q6FH83; B2R652; B4DR17
UniProt Related Accession #
O43752
GenBank Nucleotide #
NM_001286210.1
NCBI Official Full Name
syntaxin-6 isoform 2
NCBI Official Synonym Full Names
syntaxin 6
NCBI Official Symbol
STX6
UniProt Protein Name
Syntaxin-6
Protein Family
Syntaxin
UniProt Gene Name
STX6
UniProt Entry Name
STX6_HUMAN
NCBI Protein Information
syntaxin-6

UniProt Comments for STX6

STX6: Involved in intracellular vesicle trafficking. Binds EEA1. Interacts with VPS45A. Interacts with MARCH2 and MARCH3. Interacts with GOPC. Identified in a complex containing STX6, STX12, VAMP4 and VTI1A. Belongs to the syntaxin family.

Protein type: Membrane protein, integral; Vesicle

Chromosomal Location of Human Ortholog: 1q25.3

Cellular Component: clathrin-coated vesicle; early endosome; Golgi apparatus; integral to membrane; perinuclear region of cytoplasm; phagocytic vesicle; plasma membrane; SNARE complex; terminal button; trans-Golgi network; trans-Golgi network membrane

Molecular Function: protein binding; SNAP receptor activity; syntaxin binding

Biological Process: endosome organization and biogenesis; Golgi vesicle transport; intracellular protein transport; regulation of protein localization; retrograde transport, endosome to Golgi; vesicle docking; vesicle fusion
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Research Articles on STX6

1. The compartment-specific interaction of Syntaxin 6 with v-SNARES VAMP3 and VAMP4 are controlled through an ability of Syntaxin 6 to sense cholesterol levels in the trans-Golgi network and recycling endosomes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with STX6 recombinant protein

 Reference Product  PubMed Publications
 STX16 recombinant protein  >6 publications with STX6 and STX16
 VAMP3 recombinant protein  >5 publications with STX6 and VAMP3
 STX7 recombinant protein  >3 publications with STX6 and STX7
 VTI1B recombinant protein  >3 publications with STX6 and VTI1B
 VAMP4 recombinant protein  >3 publications with STX6 and VAMP4
 VTI1A recombinant protein  >2 publications with STX6 and VTI1A
 VAMP8 recombinant protein  >1 publications with STX6 and VAMP8
 STX4 recombinant protein  >1 publications with STX6 and STX4

Pathways associated with STX6 recombinant protein

 Products by Pathway  Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram

Diseases associated with STX6 recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >7 publications with STX6 and Nervous System Diseases
 Supranuclear Palsy, Progressive Antibodies  >6 publications with STX6 and Supranuclear Palsy, Progressive
 Nerve Degeneration Antibodies  >2 publications with STX6 and Nerve Degeneration
 Neurobehavioral Manifestations Antibodies  >1 publications with STX6 and Neurobehavioral Manifestations
 Ovarian Diseases Antibodies  >1 publications with STX6 and Ovarian Diseases
 Ovarian Neoplasms Antibodies  >1 publications with STX6 and Ovarian Neoplasms
 Disease Models, Animal Antibodies  >1 publications with STX6 and Disease Models, Animal
 Necrosis Antibodies  >1 publications with STX6 and Necrosis
 Inflammation Antibodies  >1 publications with STX6 and Inflammation

Organs/Tissues associated with STX6 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with STX6 and Brain
 Nerve Antibodies  >2 publications with STX6 and Nerve
 Blood Antibodies  >1 publications with STX6 and Blood
 Ovary Antibodies  >1 publications with STX6 and Ovary
 Muscle Antibodies  >1 publications with STX6 and Muscle
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