Mouse MUG1 Recombinant Protein – Cat# MBS1035048

Murinoglobulin-1 (MUG1) Mouse Recombinant Protein

Name: MUG1 Recombinant Protein; Murinoglobulin-1; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS1035048
Price: 315 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1035048

A proteinase activates the inhibitor by specific proteolysis in the bait region, which, by an unknown mechanism leads to reaction at the cysteinyl-glutamyl internal thiol ester site and to a conformational change, whereby the proteinase is trapped and/or… More details

$315 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Murinoglobulin-1 (Mug1), Recombinant Protein

Full Product Name

Recombinant Mouse Murinoglobulin-1 (Mug1), partial

Product Gene Name

Mug1 recombinant protein

Sequence

TPEISWSLRT TLSKRPEEPP RKDPSSNDPL TETIRKYFPE TWVWDIVTVN STGLAEVEMT VPDTITEWKA GALCLSNDTG LGLSSVVPLQ AFKPFFVEVS LPYSVVRGEA FMLKATVMNY LPTSMQMSVQ LEASPDFTAV PVGDDQDSYC LSANGRHTSS WLVTPKSLGN VNFSVSAEAQ QSSEPCGSEV ATVPETGRKD TVVKVLIVEP E

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

Molecular Weight

27.0 kDa

Sequence Positions

700-910aa; Partial

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for P28665

Production Note

Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Product References and Citations for Mug1 recombinant protein

Molecular characterization of the murinoglobulins.Overbergh L., Torrekens S., van Leuven F., van den Berghe H.J. Biol. Chem. 266:16903-16910(1991) Proteome-wide characterization of N-glycosylation events by diagonal chromatography.Ghesquiere B., Van Damme J., Martens L., Vandekerckhove J., Gevaert K.J. Proteome Res. 5:2438-2447(2006) Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides.Bernhard O.K., Kapp E.A., Simpson R.J.J. Proteome Res. 6:987-995(2007)

Other Notes

Small volumes of Mug1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Mug1 purchase

MBS1035048 is a recombinant protein targeting Mug1. Also known as Recombinant Mouse Murinoglobulin-1 (Mug1), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Mug1. It may not necessarily be applicable to this product.

NCBI GI #

31982171

NCBI GeneID

17836

NCBI Accession #

NP_032671.2

UniProt Primary Accession #

P28665

UniProt Secondary Accession #

Q3UNE7; Q80XE6

UniProt Related Accession #

P28665

GenBank Nucleotide #

NM_008645.3

NCBI Official Full Name

murinoglobulin-1

NCBI Official Synonym Full Names

murinoglobulin 1

NCBI Official Symbol

Mug1

UniProt Protein Name

Murinoglobulin-1

Protein Family

Meiotically up-regulated gene 1 protein

UniProt Gene Name

Mug1

UniProt Synonym Gene Names

Mug-1; MuG1

UniProt Entry Name

MUG1_MOUSE

NCBI Protein Information

murinoglobulin-1

UniProt Comments for Mug1

Mug1: A proteinase activates the inhibitor by specific proteolysis in the bait region, which, by an unknown mechanism leads to reaction at the cysteinyl-glutamyl internal thiol ester site and to a conformational change, whereby the proteinase is trapped and/or covalently bound to the inhibitor. While in the tetrameric proteinase inhibitors steric inhibition is sufficiently strong, monomeric forms need a covalent linkage between the activated glutamyl residue of the original thiol ester and a terminal amino group of a lysine or another nucleophilic group on the proteinase, for inhibition to be effective. Belongs to the protease inhibitor I39 (alpha-2- macroglobulin) family.

Cellular Component: extracellular region; extracellular space

Molecular Function: endopeptidase inhibitor activity; protease inhibitor activity; serine-type endopeptidase inhibitor activity

Biological Process: embryo implantation; negative regulation of peptidase activity

Research Articles on Mug1

1. susceptibility to T. cruzi infection of mice that are deficient only in alpha2-macroglobulins (AM-KO) or in both MAM and monomeric murinoglobulin-1 (MM-KO), relative to the wild type (WT)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with Mug1 recombinant protein

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>1 publications with Mug1 and Disease Models, Animal
Necrosis Antibodies	>1 publications with Mug1 and Necrosis

Organs/Tissues associated with Mug1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>1 publications with Mug1 and Liver