Rat CCR3 Recombinant Protein – Cat# MBS1037329

C-C Chemokine Receptor Type 3 (CCR3) Rat Recombinant Protein

Name: CCR3 Recombinant Protein; C-C Chemokine Receptor Type 3; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS1037329
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1037329

MBS1037329 is a recombinant protein targeting Ccr3. Also known as Recombinant Rat C-C chemokine receptor type 3 (Ccr3). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

C-C chemokine receptor type 3 (Ccr3), Recombinant Protein

Full Product Name

Recombinant Rat C-C chemokine receptor type 3 (Ccr3)

Product Gene Name

Ccr3 recombinant protein

Product Synonym Gene Name

Ccr3; Cmkbr3

Product Synonym Names

Recombinant C-C chemokine receptor type 3 (Ccr3); C-C chemokine receptor type 3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3; CD_antigen= CD193

Sequence

MASNEEELKT VVETFETTPY EYEWAPPCEK VSIRELGSWL LPPLYSLVFI VGLLGNMMVV LILIKYRKLQ IMTNIYLLNL AISDLLFLFT VPFWIHYVLW NEWGFGHCMC KMLSGLYYLA LYSEIFFIIL LTIDRYLAIV HAVLALRART VTFATITSII TWGFAVLAAL PEFIFHESQD NFGDLSCSPR YPEGEEDSWK RFHALRMNIF GLALPLLIMV ICYSGIIKTL LRCPNKKKHK AIQLIFVVMI VFFIFWTPYN LVLLLSAFHS TFLETSCQQS IHLDLAMQVT EVITHTHCCI NPIIYAFVGE RFRKHLRLFF HRNVAIYLRK YISFLPGEKL ERTSSVSPST GEQEISVVF

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

41,643 Da

Sequence Positions

1-359

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: 8; NC_005107.3 (132180887..132190325). Location: 8q32

3D Structure

ModBase 3D Structure for O54814

Species

Rattus norvegicus (Rat)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Ccr3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Ccr3. It may not necessarily be applicable to this product.

NCBI GI #

16758844

NCBI GeneID

117027

NCBI Accession #

NP_446410.1

UniProt Primary Accession #

O54814

UniProt Secondary Accession #

O55169

UniProt Related Accession #

O54814

GenBank Nucleotide #

NM_053958.1

NCBI Official Full Name

C-C chemokine receptor type 3

NCBI Official Synonym Full Names

chemokine (C-C motif) receptor 3

NCBI Official Symbol

Ccr3

NCBI Official Synonym Symbols

Cmkbr3

UniProt Protein Name

C-C chemokine receptor type 3

Protein Family

C-C chemokine receptor

UniProt Gene Name

Ccr3

UniProt Synonym Gene Names

Cmkbr3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3

UniProt Entry Name

CCR3_RAT

NCBI Protein Information

C-C chemokine receptor type 3; CKR3; CCR-3; CC-CKR-3; C-C CKR-3; chemokine (C-C) receptor 3

NCBI Summary for Ccr3

chemokine receptor; may have a role in inflammation and HIV infection [RGD, Feb 2006]

UniProt Comments for Ccr3

CCR3: Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. Belongs to the G-protein coupled receptor 1 family.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Receptor, cytokine; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1

Cellular Component: extracellular space; integral to membrane; plasma membrane; endosome

Molecular Function: C-C chemokine receptor activity; chemokine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of angiogenesis; mast cell chemotaxis; eosinophil chemotaxis; positive regulation of endothelial cell proliferation; inflammatory response; chemotaxis

Research Articles on Ccr3

1. CCR3 plays no role in choroidal neovascularization development.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Ccr3 recombinant protein

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram

Diseases associated with Ccr3 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>315 publications with Ccr3 and Inflammation
Hypersensitivity Antibodies	>242 publications with Ccr3 and Hypersensitivity
Asthma Antibodies	>218 publications with Ccr3 and Asthma
Lung Diseases Antibodies	>180 publications with Ccr3 and Lung Diseases
Respiratory Hypersensitivity Antibodies	>153 publications with Ccr3 and Respiratory Hypersensitivity
HIV Infections Antibodies	>121 publications with Ccr3 and HIV Infections
Necrosis Antibodies	>73 publications with Ccr3 and Necrosis
Brain Diseases Antibodies	>47 publications with Ccr3 and Brain Diseases
Dermatitis, Atopic Antibodies	>37 publications with Ccr3 and Dermatitis, Atopic
Gastrointestinal Diseases Antibodies	>32 publications with Ccr3 and Gastrointestinal Diseases