Escherichia Coli mlaE Recombinant Protein – Cat# MBS1041984

Probable Phospholipid ABC Transporter Permease Protein Mlae (mlaE) Escherichia Coli Recombinant Protein

Name: mlaE Recombinant Protein; Escherichia Coli; MyBioSource
Brand: MyBioSource
SKU: MBS1041984
Availability: InStock
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For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1041984

MBS1041984 is a recombinant protein targeting mlaE. Also known as Recombinant Escherichia coli Probable phospholipid ABC transporter permease protein mlaE (mlaE). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Probable phospholipid ABC transporter permease protein mlaE (mlaE), Recombinant Protein

Full Product Name

Recombinant Escherichia coli Probable phospholipid ABC transporter permease protein mlaE (mlaE)

Product Gene Name

mlaE recombinant protein

Product Synonym Gene Name

mlaE; yrbE

Product Synonym Names

Recombinant Probable phospholipid ABC transporter permease protein mlaE (mlaE); Probable phospholipid ABC transporter permease protein mlaE

Sequence

MLLNALASLG HKGIKTLRTF GRAGLMLFNA LVGKPEFRKH APLLVRQLYN VGVLSMLIIV VSGVFIGMVL GLQGYLVLTT YSAETSLGML VALSLLRELG PVVAALLFAG RAGSALTAEI GLMRATEQLS SMEMMAVDPL RRVISPRFWA GVISLPLLTV IFVAVGIWGG SLVGVSWKGI DSGFFWSAMQ NAVDWRMDLV NCLIKSVVFA ITVTWISLFN GYDAIPTSAG ISRATTRTVV HSSLAVLGLD FVLTALMFGN

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

27,863 Da

Sequence Positions

1-260

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

NC_000913.2 (3336488..3337270, complement)

3D Structure

ModBase 3D Structure for P64606

Species

Escherichia coli (strain K12)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of mlaE recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for mlaE. It may not necessarily be applicable to this product.

NCBI GI #

16131084

NCBI GeneID

947732

NCBI Accession #

NP_417661.1

UniProt Primary Accession #

P64606

UniProt Secondary Accession #

P45392; Q2M918

GenBank Nucleotide #

NC_000913.2

NCBI Official Full Name

ABC transporter maintaining OM lipid asymmetry, inner membrane permease protein

NCBI Official Symbol

mlaE

NCBI Official Synonym Symbols

ECK3183; JW3161; vpsB; yrbE

UniProt Protein Name

Probable phospholipid ABC transporter permease protein MlaE

Protein Family

Probable phospholipid ABC transporter permease protein

UniProt Gene Name

mlaE

UniProt Synonym Gene Names

yrbE

UniProt Entry Name

MLAE_ECOLI

NCBI Protein Information

ABC transporter maintaining OM lipid asymmetry, inner membrane permease protein

NCBI Summary for mlaE

YrbE is in an operon with ABC transporter homologs and may be a permease protein. [More information is available at EcoGene: EG12800]. Yrbe is the membrane component of a predicted ABC superfamily toluene efflux transporter. [More information is available at EcoCyc: EG12800].

UniProt Comments for mlaE

Function: Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Ref.4

Subunit structure: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and a periplamic solute-binding protein (MlaD)

Probable. Ref.4

Subcellular location: Cell inner membrane; Multi-pass membrane protein Ref.4.

Disruption phenotype: Mutation confers sensitivity to SDS-EDTA and leads to accumulation of phospholipid in the outer leaflet of the outer membrane. Ref.4

Sequence similarities: Belongs to the MlaE permease family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with mlaE recombinant protein

Reference Product	PubMed Publications
murA recombinant protein	>1 publications with mlaE and murA
yrbA recombinant protein	>1 publications with mlaE and yrbA

Pathways associated with mlaE recombinant protein

Products by Pathway	Pathway Diagram
Putative ABC Transport System Pathway antibodies	Putative ABC Transport System Pathway Diagram