Rat LGALS3 Recombinant Protein – Cat# MBS1045552

Galectin-3 (LGALS3) Rat Recombinant Protein

Name: LGALS3 Recombinant Protein; Galectin-3; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS1045552
Price: 455 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1045552

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil… More details

$455 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Galectin-3 (Lgals3), Recombinant Protein

Full Product Name

Recombinant Rat Galectin-3 (Lgals3)

Product Gene Name

Lgals3 recombinant protein

Product Synonym Names

Galectin-3; Gal-3; 35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; IgE-binding protein; Laminin-binding protein; Lectin L-29; Mac-2 antigen

Sequence

ADGFSLNDAL AGSGNPNPQG WPGAWGNQPG AGGYPGASYP GAYPGQAPPG GYPGQAPPSA YPGPTGPSAY PGPTAPGAYP GPTAPGAFPG QPGGPGAYPS APGAYPSAPG AYPATGPFGA PTGPLTVPYD MPLPGGVMPR MLITIIGTVK PNANSITLNF KKGNDIAFHF NPRFNENNRR VIVCNTKQDN NWGREERQSA FPFESGKPFK IQVLVEADHF KVAVNDVHLL QYNHRMKNLR EISQLGIIGD ITLTSASHAM I

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

31.1 kDa

Sequence Positions

2-262aa; Full Length of Mature Protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for P08699

Species

Rattus norvegicus (Rat)

Product Categories/Family for Lgals3 recombinant protein

Neuroscience

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Lgals3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Lgals3 purchase

MBS1045552 is a recombinant protein targeting Lgals3. Also known as Recombinant Rat Galectin-3 (Lgals3). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Lgals3. It may not necessarily be applicable to this product.

NCBI GI #

13929190

NCBI GeneID

83781

NCBI Accession #

NP_114020.1

UniProt Primary Accession #

P08699

UniProt Related Accession #

P08699

GenBank Nucleotide #

NM_031832.1

NCBI Official Full Name

galectin-3

NCBI Official Synonym Full Names

lectin, galactoside-binding, soluble, 3

NCBI Official Symbol

Lgals3

NCBI Official Synonym Symbols

gal-3

UniProt Protein Name

Galectin-3

UniProt Synonym Protein Names

35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; IgE-binding protein; Laminin-binding protein; Lectin L-29; Mac-2 antigen

UniProt Gene Name

Lgals3

UniProt Synonym Gene Names

Gal-3; CBP 35

UniProt Entry Name

LEG3_RAT

NCBI Protein Information

galectin-3; CBP 35; lectin L-29; 35 kDa lectin; mac-2 antigen; IgE binding protein; igE-binding protein; laminin-binding protein; galactose-specific lectin 3; carbohydrate-binding protein 35; lectin, galactose binding, soluble 3; lectin galactoside-binding soluble 3 protein

NCBI Summary for Lgals3

lectin molecule that binds IgE; may have role in immune function [RGD, Feb 2006]

UniProt Comments for Lgals3

Galectin-3: galactose-specific lectin which binds IgE. Expressed at a high level in the colonic epithelium. Also abundant in activated macrophages.

Protein type: Motility/polarity/chemotaxis; Cell surface; Extracellular matrix

Cellular Component: extracellular matrix; spliceosome; proteinaceous extracellular matrix; extracellular space; cell surface; membrane; mitochondrial inner membrane; cytoplasm; plasma membrane; immunological synapse; nucleus; external side of plasma membrane

Molecular Function: monosaccharide binding; advanced glycation end-product receptor activity; laminin binding; IgE binding; disaccharide binding; chemoattractant activity

Biological Process: neutrophil chemotaxis; extracellular matrix organization and biogenesis; positive regulation of serotonin secretion; RNA splicing; negative regulation of endocytosis; regulation of T cell proliferation; negative regulation of T cell receptor signaling pathway; signal transduction; macrophage chemotaxis; monocyte chemotaxis; positive regulation of angiogenesis; positive chemotaxis; epithelial cell differentiation; positive regulation of cell proliferation; eosinophil chemotaxis; innate immune response; mRNA processing; skeletal development; negative regulation of apoptosis

Research Articles on Lgals3

1. galectin-3 is activated in microglia and macrophages according to the progression of glioma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Lgals3 recombinant protein

Reference Product	PubMed Publications
Lgals3bp recombinant protein	>36 publications with Lgals3 and Lgals3bp
Egfr recombinant protein	>27 publications with Lgals3 and Egfr
Kras recombinant protein	>9 publications with Lgals3 and Kras
S100a6 recombinant protein	>6 publications with Lgals3 and S100a6
Gemin4 recombinant protein	>5 publications with Lgals3 and Gemin4
Anxa2 recombinant protein	>3 publications with Lgals3 and Anxa2
Nras recombinant protein	>2 publications with Lgals3 and Nras
Hras recombinant protein	>2 publications with Lgals3 and Hras
Sufu recombinant protein	>1 publications with Lgals3 and Sufu

Pathways associated with Lgals3 recombinant protein

Products by Pathway	Pathway Diagram
Advanced Glycosylation Endproduct Receptor Signaling Pathway antibodies	Advanced Glycosylation Endproduct Receptor Signaling Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram

Diseases associated with Lgals3 recombinant protein

Disease Name	Pubmed Publications
Neoplasms Antibodies	>831 publications with Lgals3 and Neoplasms
Carcinoma Antibodies	>499 publications with Lgals3 and Carcinoma
Inflammation Antibodies	>221 publications with Lgals3 and Inflammation
Adenocarcinoma Antibodies	>216 publications with Lgals3 and Adenocarcinoma
Neoplasm Metastasis Antibodies	>138 publications with Lgals3 and Neoplasm Metastasis
Adenoma Antibodies	>134 publications with Lgals3 and Adenoma
Disease Models, Animal Antibodies	>131 publications with Lgals3 and Disease Models, Animal
Nervous System Diseases Antibodies	>126 publications with Lgals3 and Nervous System Diseases
Fibrosis Antibodies	>108 publications with Lgals3 and Fibrosis
Breast Neoplasms Antibodies	>105 publications with Lgals3 and Breast Neoplasms

Organs/Tissues associated with Lgals3 recombinant protein

Organ/Tissue Name	Pubmed Publications
Heart Antibodies	>125 publications with Lgals3 and Heart
Brain Antibodies	>123 publications with Lgals3 and Brain
Lung Antibodies	>105 publications with Lgals3 and Lung
Colon Antibodies	>81 publications with Lgals3 and Colon
Prostate Antibodies	>50 publications with Lgals3 and Prostate
Embryonic Tissue Antibodies	>42 publications with Lgals3 and Embryonic Tissue
Eye Antibodies	>41 publications with Lgals3 and Eye
Connective Tissue Antibodies	>37 publications with Lgals3 and Connective Tissue
Spleen Antibodies	>30 publications with Lgals3 and Spleen
Pancreas Antibodies	>22 publications with Lgals3 and Pancreas