Hyaluronidase (HAASE) ELISA Kit for Human

Name: Human HAASE ELISA Kit; Hyaluronidase; MyBioSource
Brand: MyBioSource
SKU: MBS010472
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS010472

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of HAASE (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Hyaluronidase (HAASE), ELISA Kit

Full Product Name

Human Hyaluronidase ELISA Kit

Product Gene Name

HAASE elisa kit

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, Plasma and Tissue Homogenate

Detection Range

15.6 ng/ml - 500 ng/ml.

Sensitivity

2.0 ng/ml.

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

46,501 Da

Chromosome Location

Chromosome: 3; NC_000003.11 (50330259..50336899, complement). Location: 3p21.3

OMIM

604038

3D Structure

ModBase 3D Structure for O43820

Other Notes

Small volumes of HAASE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HAASE purchase

MBS010472 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Hyaluronidase (HAASE) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HAASE. The ELISA analytical biochemical technique of the MBS010472 kit is based on HAASE antibody-HAASE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HAASE antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HAASE. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for HAASE. It may not necessarily be applicable to this product.

NCBI GI #

2935328

NCBI GeneID

8372

NCBI Accession #

AAC70915.1

UniProt Primary Accession #

O43820

UniProt Secondary Accession #

O60540; Q8NFK2; Q8NFK3; Q8NFK4; Q96E56; Q9BRW9

UniProt Related Accession #

O43820

NCBI Official Full Name

hyaluronidase

NCBI Official Synonym Full Names

hyaluronoglucosaminidase 3

NCBI Official Symbol

HYAL3

NCBI Official Synonym Symbols

LUCA3; HYAL-3; LUCA-3

UniProt Protein Name

Hyaluronidase-3

UniProt Synonym Protein Names

Hyaluronoglucosaminidase-3; Lung carcinoma protein 3

Protein Family

Hyaluronidase

UniProt Gene Name

HYAL3

UniProt Synonym Gene Names

LUCA3; Hyal-3; LuCa-3

UniProt Entry Name

HYAL3_HUMAN

NCBI Protein Information

hyaluronidase-3; lung carcinoma protein 3

NCBI Summary for HAASE

This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]

UniProt Comments for HAASE

HYAL3: a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]

Protein type: Secreted, signal peptide; EC 3.2.1.35; Secreted; Hydrolase

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: lysosome; extracellular region; cytoplasmic vesicle

Molecular Function: viral receptor activity; hyaluronoglucuronidase activity; hyalurononglucosaminidase activity

Biological Process: response to antibiotic; cartilage development; response to virus; carbohydrate metabolic process; inflammatory response; hyaluronan catabolic process

Research Articles on HAASE

1. mutations of the HYAL3 gene are rare in Chinese lung squamous cell carcinoma patients and might contribute to lymph node metastasis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HAASE elisa kit

Reference Product	PubMed Publications
IFRD2 elisa kit	>1 publications with HAASE and IFRD2

Pathways associated with HAASE elisa kit

Products by Pathway	Pathway Diagram
Chondroitin Sulfate Degradation Pathway antibodies	Chondroitin Sulfate Degradation Pathway Diagram
Chondroitin Sulfate Degradation Pathway antibodies	Chondroitin Sulfate Degradation Pathway Diagram
Dermatan Sulfate Degradation Pathway antibodies	Dermatan Sulfate Degradation Pathway Diagram
Dermatan Sulfate Degradation Pathway antibodies	Dermatan Sulfate Degradation Pathway Diagram
Glycosaminoglycan Degradation Pathway antibodies	Glycosaminoglycan Degradation Pathway Diagram
Glycosaminoglycan Degradation Pathway antibodies	Glycosaminoglycan Degradation Pathway Diagram

Diseases associated with HAASE elisa kit

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>2 publications with HAASE and Disease Models, Animal
Necrosis Antibodies	>2 publications with HAASE and Necrosis
Genital Diseases, Male Antibodies	>1 publications with HAASE and Genital Diseases, Male
Liver Neoplasms Antibodies	>1 publications with HAASE and Liver Neoplasms
Kidney Diseases Antibodies	>1 publications with HAASE and Kidney Diseases
Inflammation Antibodies	>1 publications with HAASE and Inflammation

Organs/Tissues associated with HAASE elisa kit

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>4 publications with HAASE and Lung
Kidney Antibodies	>4 publications with HAASE and Kidney
Blood Antibodies	>3 publications with HAASE and Blood
Placenta Antibodies	>2 publications with HAASE and Placenta
Embryonic Tissue Antibodies	>2 publications with HAASE and Embryonic Tissue
Testis Antibodies	>1 publications with HAASE and Testis
Brain Antibodies	>1 publications with HAASE and Brain