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Probable Early E4 17 Kda Protein (E4-ORF6/7) Human Adenovirus C Serotype 2 Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1047576

MBS1047576 is a recombinant protein targeting E4-ORF6/7. Also known as Recombinant Human adenovirus C serotype 2 Probable early E4 17 kDa protein. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$800 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Probable early E4 17 kDa protein (E4-ORF6/7), Recombinant Protein
Full Product Name
Recombinant Human adenovirus C serotype 2 Probable early E4 17 kDa protein
Sequence
MTTSGVPFGM TLRPTRSRLS RRTPYSRDRL PPFETETRAT ILEDHPLLPE CNTLTMHNAW TSPSPPVEQP QVGQQPVAQQ LDSDMNLSEL PGEFINITDE RLARQETVWN ITPKNMSVTH DMMLFKASRG ERTVYSVCWE GGGRLNTRVL
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
17,054 Da
Sequence Positions
1-150, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P03238
Species
Human adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of E4-ORF6/7 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for E4-ORF6/7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
GenBank Nucleotide #
NCBI Official Full Name
E4 ORF6/7
UniProt Protein Name
Early 4 ORF6/7 control protein
UniProt Synonym Protein Names
Early E4 17 kDa protein
UniProt Gene Name
E4-ORF6/7
UniProt Synonym Gene Names
E4-ORF6/7

UniProt Comments for E4-ORF6/7

Modulates viral and host transcriptional activity to promote viral genome replication. Stimulates viral E2a promoter activity by binding and inducing dimerization of host E2F. During viral infection E1A protein binds to cellular retinablastoma (RB) family members and disociates these repressors from a complex with E2F proteins. Free E2F is then bound to E4orf6/7 which leads to transactivation of viral E2 promoter, and cellular promoters such as E2F-1 promoter. Activation of cellular E2F targets promote cell cycle S phase and thereby possibly favorises viral DNA replication process.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with E4-ORF6/7 recombinant protein

 Reference Product  PubMed Publications
 FLNA recombinant protein  >12 publications with E4-ORF6/7 and FLNA
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