Escherichia Coli cusS Recombinant Protein – Cat# MBS1052619

Sensor Kinase Cuss (cusS) Escherichia Coli Recombinant Protein

Name: cusS Recombinant Protein; Sensor Kinase Cuss; Escherichia Coli; MyBioSource
Brand: MyBioSource
SKU: MBS1052619
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1052619

MBS1052619 is a recombinant protein targeting cusS. Also known as Recombinant Escherichia coli Sensor kinase CusS (cusS). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Sensor kinase CusS (cusS), Recombinant Protein

Full Product Name

Recombinant Escherichia coli Sensor kinase CusS (cusS)

Product Gene Name

cusS recombinant protein

Product Synonym Gene Name

cusS; ybcZ

Product Synonym Names

Recombinant Sensor kinase CusS (cusS); Sensor kinase CusS EC= 2.7.13.3

Sequence

MVSKPFQRPF SLATRLTFFI SLATIAAFFA FAWIMIHSVK VHFAEQDIND LKEISATLER VLNHPDETQA RRLMTLEDIV SGYSNVLISL ADSQGKTVYH SPGAPDIREF TRDAIPDKDA QGGEVYLLSG PTMMMPGHGH GHMEHSNWRM INLPVGPLVD GKPIYTLYIA LSIDFHLHYI NDLMNKLIMT ASVISILIVF IVLLAVHKGH APIRSVSRQI QNITSKDLDV RLDPQTVPIE LEQLVLSFNH MIERIEDVFT RQSNFSADIA HEIRTPITNL ITQTEIALSQ SRSQKELEDV LYSNLEELTR MAKMVSDMLF LAQADNNQLI PEKKMLNLAD EVGKVFDFFE ALAEDRGVEL RFVGDKCQVA GDPLMLRRAL SNLLSNALRY TPTGETIVVR CQTVDHLVQV IVENPGTPIA PEHLPRLFDR FYRVDPSRQR KGEGSGIGLA IVKSIVVAHK GTVAVTSDAR GTRFVITLPA

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

53,738 Da

Sequence Positions

1-480

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

NC_000913.2 (592551..593993, complement)

3D Structure

ModBase 3D Structure for P77485

Species

Escherichia coli (strain K12)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of cusS recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for cusS. It may not necessarily be applicable to this product.

NCBI GI #

16128553

NCBI GeneID

945978

NCBI Accession #

NP_415102.1

UniProt Primary Accession #

P77485

UniProt Secondary Accession #

Q9R7T9; Q9R7U0

GenBank Nucleotide #

NC_000913.2

NCBI Official Full Name

sensory histidine kinase in two-component regulatory system with CusR, senses copper ions

NCBI Official Symbol

cusS

NCBI Official Synonym Symbols

ECK0562; JW5082; silS; ybcZ

UniProt Protein Name

Sensor kinase CusS

Protein Family

Sensor kinase

UniProt Gene Name

cusS

UniProt Synonym Gene Names

ybcZ

UniProt Entry Name

CUSS_ECOLI

NCBI Protein Information

sensory histidine kinase in two-component regulatory system with CusR, senses copper ions

NCBI Summary for cusS

The cusABFCRS gene cluster has similarity to a gene cluster contained on a silver resistance plasmid from a clinical Salmonella isolate . [More information is available at EcoCyc: G6318].

UniProt Comments for cusS

Function: Member of the two-component regulatory system CusS/CusR. Copper ion sensor. Could also be a silver ion sensor. Activates CusR by phosphorylation. Ref.1 Ref.6 Ref.7 Ref.8

Catalytic activity: ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.

Subcellular location: Cell inner membrane; Multi-pass membrane protein.

Post-translational modification: Autophosphorylated. Ref.8

Miscellaneous: The cus system plays an important role in copper tolerance under anaerobic growth and, under extreme copper stress, in aerobic growth.

Sequence similarities: Contains 1 HAMP domain.Contains 1 histidine kinase domain.

Research Articles on cusS

1. These results show a metal-dependent mechanism of CusS activation and suggest an absolute requirement for CusS in Cu(I)- and Ag(I)-dependent upregulation of cusCFBA expression in Escherichia coli.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with cusS recombinant protein

Reference Product	PubMed Publications
cusR recombinant protein	>6 publications with cusS and cusR
cueR recombinant protein	>2 publications with cusS and cueR
yedW recombinant protein	>2 publications with cusS and yedW
basR recombinant protein	>1 publications with cusS and basR
cusC recombinant protein	>1 publications with cusS and cusC

Pathways associated with cusS recombinant protein

Products by Pathway	Pathway Diagram
CusS-CusR (copper Tolerance) Two-component Regulatory System Pathway antibodies	CusS-CusR (copper Tolerance) Two-component Regulatory System Pathway Diagram
CusS-CusR (copper Tolerance) Two-component Regulatory System Pathway antibodies	CusS-CusR (copper Tolerance) Two-component Regulatory System Pathway Diagram
CusSR Two-Component Signal Transduction System Pathway antibodies	CusSR Two-Component Signal Transduction System Pathway Diagram
Two-component System Pathway antibodies	Two-component System Pathway Diagram
Two-component System Pathway antibodies	Two-component System Pathway Diagram