Human FAM20B Recombinant Protein – Cat# MBS1061277

Glycosaminoglycan Xylosylkinase (FAM20B) Human Recombinant Protein

Name: FAM20B Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1061277
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1061277

MBS1061277 is a recombinant protein targeting FAM20B. Also known as Recombinant Human Glycosaminoglycan xylosylkinase (FAM20B). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. FAM20B; KIAA0475 More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Glycosaminoglycan xylosylkinase (FAM20B), Recombinant Protein

Full Product Name

Recombinant Human Glycosaminoglycan xylosylkinase (FAM20B)

Product Gene Name

FAM20B recombinant protein

Product Synonym Gene Name

FAM20B; KIAA0475

Product Synonym Names

Glycosaminoglycan xylosylkinase; EC=2.7.1.-; Protein FAM20B; Xylose kinase

Sequence

MKLKQRVVLL AILLVIFIFT KVFLIDNLDT SAANREDQRA FHRMMTGLRV ELAPKLDHTL QSPWEIAAQW VVPREVYPEE TPELGAVMHA MATKKIIKAD VGYKGTQLKA LLILEGGQKV VFKPKRYSRD HVVEGEPYAG YDRHNAEVAA FHLDRILGFH RAPLVVGRFV NLRTEIKPVA TEQLLSTFLT VGNNTCFYGK CYYCRETEPA CADGDIMEGS VTLWLPDVWP LQKHRHPWGR TYREGKLARW EYDESYCDAV KKTSPYDSGP RLLDIIDTAV FDYLIGNADR HHYESFQDDE GASMLILLDN AKSFGNPSLD ERSILAPLYQ CCIIRVSTWN RLNYLKNGVL KSALKSAMAH DPISPVLSDP HLDAVDQRLL SVLATVKQCT DQFGMDTVLV EDRMPLSHL

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

46,432 Da

Sequence Positions

1-409

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

611063

3D Structure

ModBase 3D Structure for O75063

Species

Homo sapiens (Human)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of FAM20B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FAM20B. It may not necessarily be applicable to this product.

NCBI GI #

7662150

NCBI GeneID

9917

NCBI Accession #

NP_055679.1

UniProt Primary Accession #

O75063

UniProt Secondary Accession #

Q5W0C3; Q5W0C4

UniProt Related Accession #

O75063

GenBank Nucleotide #

NM_014864.3

NCBI Official Full Name

glycosaminoglycan xylosylkinase

NCBI Official Synonym Full Names

family with sequence similarity 20, member B

NCBI Official Symbol

FAM20B

NCBI Official Synonym Symbols

gxk1

UniProt Protein Name

Glycosaminoglycan xylosylkinase

UniProt Synonym Protein Names

Protein FAM20B; Xylose kinase

Protein Family

Glycosaminoglycan xylosylkinase

UniProt Gene Name

FAM20B

UniProt Synonym Gene Names

KIAA0475

UniProt Entry Name

XYLK_HUMAN

NCBI Protein Information

glycosaminoglycan xylosylkinase; xylose kinase

UniProt Comments for FAM20B

FAM20B: Responsible for the 2-O-phosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature GAG chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG- protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1- O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-o-phosphorylation may influence the catalytic activity of B3GAT3 (GlcAT-I) which completes the precursor tetrasaccharide of GAG-protein linkage regions on which the repeating disaccharide region is synthesized. Belongs to the FAM20 family.

Protein type: Membrane protein, integral; EC 2.7.1.-

Chromosomal Location of Human Ortholog: 1q25

Cellular Component: Golgi membrane; nucleoplasm; Golgi apparatus; integral to membrane

Molecular Function: kinase activity; phosphotransferase activity, alcohol group as acceptor; ATP binding

Biological Process: phosphorylation

Research Articles on FAM20B

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with FAM20B recombinant protein

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>4 publications with FAM20B and Bone
Liver Antibodies	>2 publications with FAM20B and Liver
Kidney Antibodies	>1 publications with FAM20B and Kidney
Connective Tissue Antibodies	>1 publications with FAM20B and Connective Tissue
Muscle Antibodies	>1 publications with FAM20B and Muscle
Skin Antibodies	>1 publications with FAM20B and Skin