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Fatty Acid Desaturase 2 (FADS2) Bovine Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1065277

MBS1065277 is a recombinant protein targeting FADS2. Also known as Recombinant Bovine Fatty acid desaturase 2 (FADS2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. FADS2 More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Fatty acid desaturase 2 (FADS2), Recombinant Protein
Full Product Name
Recombinant Bovine Fatty acid desaturase 2 (FADS2)
Product Gene Name
FADS2 recombinant protein
Product Synonym Gene Name
Recombinant Fatty acid desaturase 2 (FADS2); Fatty acid desaturase 2 EC= 1.14.19.-; Delta(6) fatty acid desaturase; D6D; Delta(6) desaturase; Delta-6 desaturase
Sequence
MGKGGNQDEG ATELEAPMPT FRWEEIQKHN LRTDKWLVID RKVYNITKWS SRHPGGQRVI GHYAGEDATD AFLAFHRNLD FVRKFMKPLL IGELAPEEPS QDRGKNSQIT EDFRALRKTA EDMNLFKSNQ LFFLLHLAHI IAMESIAWFT LFYFGNGWIP TIITAFVLAT SQAQAGWLQH DYGHLSVYKK SMWNHIVHKF VIGHLKGASA NWWNHRHFQH HAKPNIFHKD PDVNMLHVFV LGEWQPIEYG KKKLKYLPYN HQHEYFFLIG PPLLIPLYFQ YQIIMTMIVR KYWADLAWAI SYYTRFFITY IPFYGVLGSI LFLNFIRFLE SHWFVWVTQM NHIVMEIDRE PYRDWFSSQL AATCNVEQSF FNDWFSGHLN FQIEHHLFPT MPRHNLHKIA PLVRSLCAKH GIEYQEKPLL RALQDIIGSL RKSGQLWLDA YLHK
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
52,533 Da
Sequence Positions
1-444
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: 29; AC_000186.1 (41045232..41082249). Location: chromosome: 29
3D Structure
ModBase 3D Structure for A4FV48
Species
Bos taurus (Bovine)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of FADS2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FADS2. It may not necessarily be applicable to this product.

NCBI GI #
134085894
NCBI GeneID
521822
NCBI Accession #
NP_001076913.1
UniProt Primary Accession #
A4FV48
UniProt Related Accession #
A4FV48
GenBank Nucleotide #
NM_001083444.1
NCBI Official Full Name
fatty acid desaturase 2
NCBI Official Synonym Full Names
fatty acid desaturase 2
NCBI Official Symbol
FADS2
UniProt Protein Name
Fatty acid desaturase 2
UniProt Synonym Protein Names
Delta(6) fatty acid desaturase
Protein Family
Fatty acid desaturase
UniProt Gene Name
FADS2
UniProt Synonym Gene Names
D6D; Delta(6) desaturase
UniProt Entry Name
FADS2_BOVIN
NCBI Protein Information
fatty acid desaturase 2; D6D; delta-6 desaturase; delta(6) desaturase; delta-6 fatty acid desaturase; delta(6) fatty acid desaturase

UniProt Comments for FADS2

Function: Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma-linoleic acid (GLA) (18:3n-6) and stearidonic acid (18:4n-3) respectively and as well other desaturation steps. Highly unsaturated fatty acids (HUFA) play pivotal roles in many biological functions

By similarity.

Pathway: Lipid metabolism; polyunsaturated fatty acid biosynthesis.

Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein

Potential.

Domain: The histidine box domains may contain the active site and/or be involved in metal ion binding.

Sequence similarities: Belongs to the fatty acid desaturase family.Contains 1 cytochrome b5 heme-binding domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with FADS2 recombinant protein

 Products by Pathway  Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies  Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 Alpha-Linolenic Acid Metabolism Pathway antibodies  Alpha-Linolenic Acid Metabolism Pathway Diagram
 Alpha-Linolenic Acid Metabolism Pathway antibodies  Alpha-Linolenic Acid Metabolism Pathway Diagram

Diseases associated with FADS2 recombinant protein

 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >21 publications with FADS2 and Fatty Liver
 Cardiovascular Diseases Antibodies  >17 publications with FADS2 and Cardiovascular Diseases
 Inflammation Antibodies  >13 publications with FADS2 and Inflammation
 Coronary Artery Disease Antibodies  >8 publications with FADS2 and Coronary Artery Disease
 Insulin Resistance Antibodies  >8 publications with FADS2 and Insulin Resistance
 Skin Diseases Antibodies  >6 publications with FADS2 and Skin Diseases
 Atherosclerosis Antibodies  >5 publications with FADS2 and Atherosclerosis
 Liver Diseases Antibodies  >4 publications with FADS2 and Liver Diseases
 Neoplasms Antibodies  >4 publications with FADS2 and Neoplasms
 Fibrosis Antibodies  >2 publications with FADS2 and Fibrosis
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