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Transformer-2 Sex-Determining Protein (tra2) Drosophila Virilis Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1069705

MBS1069705 is a recombinant protein targeting tra2. Also known as Recombinant Drosophila virilis Transformer-2 sex-determining protein (tra2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$955 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Transformer-2 sex-determining protein (tra2), Recombinant Protein
Full Product Name
Recombinant Drosophila virilis Transformer-2 sex-determining protein (tra2)
Product Gene Name
Sequence
MSTGLVNARE KEYLHLHRID KHKCSHSSAT SSPSSAASSE SSRTRQRRSD GEVYGSRHNN YKSSSQHRRR SRSGSDSPQV RHYSGRTSRD RQRMRQARDH PQASRCIGVF GLNTNTTQQK VRELFNKFGP IERIQMVIDA HTHRSRGFCF IYFENLGDAR VAKDACTGME VDGRRIRVDY SITQRAHTPT PGVYMGRPSR PLGRRSRERD YSTRDTSRSR RRHRDESSSV SPYDSNRRKY RSRHRYDRSR SRTRSYSRSR SPRKPVRVQS RY
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
26,622 Da
Sequence Positions
1-272, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for O02008
Species
Drosophila virilis (Fruit fly)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of tra2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for tra2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tra2, isoform D
NCBI Official Symbol
Dvir ra2
NCBI Official Synonym Symbols
DvirGJ21740; dvir_GLEANR_7073; GJ21740; tra-2; tra2; Tra2
UniProt Protein Name
Transformer-2 sex-determining protein
Protein Family
UniProt Gene Name
tra2
UniProt Synonym Gene Names
tra-2
NCBI Protein Information
GJ21740 gene product from transcript GJ21740-RD

UniProt Comments for tra2

Required for female sex determination in somatic cells and for spermatogenesis in male germ cells. Positive regulator of female-specific splicing and/or polyadenylation of doublesex (dsx) pre-mRNA. Splicing requires an enhancer complex, dsxRE (dsx repeat element: which contains six copies of a 13-nucleotide repeat and a purine-rich enhancer (PRE)). DsxRE is formed through cooperative interactions between tra, tra2 and the sr proteins, and these interactions require both the repeat sequences and PRE. PRE is required for specific binding of tra2 to the dsxRE. Protein-RNA and protein-protein interactions are involved in tra-2 dependent activation and repression of alternative splicing ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with tra2 recombinant protein

 Reference Product  PubMed Publications
 FLNA recombinant protein  >12 publications with tra2 and FLNA
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