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Lumican (LUM) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1072244

MBS1072244 is a recombinant protein targeting Lum. Also known as Recombinant Rat Lumican. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$455 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Lumican, Recombinant Protein
Full Product Name
Recombinant Rat Lumican
Product Gene Name
Lum recombinant protein
Product Synonym Names
Keratan sulfate proteoglycan lumican; KSPG lumican
Sequence
QYYDYDAPLF MYGELSPNCA PECNCPHSYP TAMYCDDLKL KSVPMVPPGI KYLYLRNNQI DHIDEKAFEN VTDLQWLILD HNLLENSKIK GKVFSKLKQL KKLHINYNNL TESVGPLPKS LQDLQLANNK ISKLGSFDGL VNLTFIYLQH NQLKEEAVSA SLKGLKSLEY LDLSFNQMSK LPAGLPTSLL TLYLDNNKIT NIPDEYFNRF TGLQYLRLSH NELADSGVPG NSFNISSLLE LDLSYNKLKS IPTVNENLEN YYLEVNKLEK FDVKSFCKIL GPLSYSKIKH LRLDGNPLTQ SSLPPDMYEC LRVANEITVN
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Molecular Weight
40.5 kDa
Sequence Positions
19-338aa; Full Length
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P51886
Species
Rat

Product Categories/Family for Lum recombinant protein

Signal Transduction
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

SDS-PAGE of Lum recombinant protein

Rat LUM Recombinant Protein – Cat# MBS1072244

Product References and Citations for Lum recombinant protein

"Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues." Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C., Olsen J.V. Nat. Commun. 3:876-876(2012)

Other Notes

Small volumes of Lum recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Lum. It may not necessarily be applicable to this product.

NCBI GI #
13591983
NCBI GeneID
81682
NCBI Accession #
NP_112312.1
UniProt Primary Accession #
P51886
UniProt Related Accession #
P51886
GenBank Nucleotide #
NM_031050.1
NCBI Official Full Name
lumican
NCBI Official Synonym Full Names
lumican
NCBI Official Symbol
Lum
UniProt Protein Name
Lumican
UniProt Synonym Protein Names
Keratan sulfate proteoglycan lumican; KSPG lumican
Protein Family
Lumican
UniProt Gene Name
Lum
UniProt Synonym Gene Names
Lcn; Ldc; KSPG lumican
UniProt Entry Name
LUM_RAT
NCBI Protein Information
lumican

NCBI Summary for Lum

member of leucine-rich proteoglycan family; may play a role in immature and transient fibrosis of acute pancreatitis [RGD, Feb 2006]

UniProt Comments for Lum

LUM: a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008]

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular matrix; extracellular space; fibrillar collagen; proteinaceous extracellular matrix

Molecular Function: collagen binding

Biological Process: axonogenesis; cartilage development; collagen fibril organization; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transforming growth factor-beta1 production; response to organic cyclic substance; visual perception
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Research Articles on Lum

1. These findings indicate that lumican is transiently synthesized by acinar cells and fibroblasts in acute pancreatitis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Lum recombinant protein

 Reference Product  PubMed Publications
 Dcn recombinant protein  >20 publications with Lum and Dcn
 Kera recombinant protein  >12 publications with Lum and Kera
 Fmod recombinant protein  >10 publications with Lum and Fmod
 Prelp recombinant protein  >3 publications with Lum and Prelp
 Ogn recombinant protein  >2 publications with Lum and Ogn
 Omd recombinant protein  >1 publications with Lum and Omd

Pathways associated with Lum recombinant protein

 Products by Pathway  Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 Integrin Cell Surface Interactions Pathway antibodies  Integrin Cell Surface Interactions Pathway Diagram
 Keratan Sulfate Biosynthesis Pathway antibodies  Keratan Sulfate Biosynthesis Pathway Diagram
 Keratan Sulfate Degradation Pathway antibodies  Keratan Sulfate Degradation Pathway Diagram
 Keratan Sulfate/keratin Metabolism Pathway antibodies  Keratan Sulfate/keratin Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram
 Proteoglycans In Cancer Pathway antibodies  Proteoglycans In Cancer Pathway Diagram
 Proteoglycans In Cancer Pathway antibodies  Proteoglycans In Cancer Pathway Diagram

Diseases associated with Lum recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >267 publications with Lum and Nervous System Diseases
 Brain Diseases Antibodies  >156 publications with Lum and Brain Diseases
 Inflammation Antibodies  >81 publications with Lum and Inflammation
 Breast Neoplasms Antibodies  >74 publications with Lum and Breast Neoplasms
 Disease Models, Animal Antibodies  >74 publications with Lum and Disease Models, Animal
 Kidney Diseases Antibodies  >65 publications with Lum and Kidney Diseases
 Hematologic Diseases Antibodies  >64 publications with Lum and Hematologic Diseases
 Liver Diseases Antibodies  >56 publications with Lum and Liver Diseases
 Necrosis Antibodies  >54 publications with Lum and Necrosis
 Adenocarcinoma Antibodies  >48 publications with Lum and Adenocarcinoma

Organs/Tissues associated with Lum recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >169 publications with Lum and Lung
 Brain Antibodies  >139 publications with Lum and Brain
 Kidney Antibodies  >98 publications with Lum and Kidney
 Heart Antibodies  >89 publications with Lum and Heart
 Eye Antibodies  >86 publications with Lum and Eye
 Connective Tissue Antibodies  >42 publications with Lum and Connective Tissue
 Embryonic Tissue Antibodies  >30 publications with Lum and Embryonic Tissue
 Prostate Antibodies  >23 publications with Lum and Prostate
 Adipose Tissue Antibodies  >18 publications with Lum and Adipose Tissue
 Colon Antibodies  >18 publications with Lum and Colon
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