Human LRRN2 Recombinant Protein – Cat# MBS1076996

Leucine-Rich Repeat Neuronal Protein 2 (LRRN2) Human Recombinant Protein

Name: LRRN2 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1076996
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1076996

MBS1076996 is a recombinant protein targeting LRRN2. Also known as Recombinant Human Leucine-rich repeat neuronal protein 2 (LRRN2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Leucine-rich repeat neuronal protein 2 (LRRN2), Recombinant Protein

Full Product Name

Recombinant Human Leucine-rich repeat neuronal protein 2 (LRRN2)

Product Gene Name

LRRN2 recombinant protein

Product Synonym Gene Name

LRRN2; GAC1; LRRN5; UNQ256/PRO293

Product Synonym Names

Leucine-rich repeat neuronal protein 2; Glioma amplified on chromosome 1 protein; Leucine-rich repeat neuronal protein 5

Sequence

AV PVVPWHVPCP PQCACQIRPW YTPRSSYREA TTVDCNDLFL TAVPPALPAG TQTLLLQSNS IVRVDQSELG YLANLTELDL SQNSFSDARD CDFHALPQLL SLHLEENQLT RLEDHSFAGL ASLQELYLNH NQLYRIAPRA FSGLSNLLRL HLNSNLLRAI DSRWFEMLPN LEILMIGGNK VDAILDMNFR PLANLRSLVL AGMNLREISD YALEGLQSLE SLSFYDNQLA RVPRRALEQV PGLKFLDLNK NPLQRVGPGD FANMLHLKEL GLNNMEELVS IDKFALVNLP ELTKLDITNN PRLSFIHPRA FHHLPQMETL MLNNNALSAL HQQTVESLPN LQEVGLHGNP IRCDCVIRWA NATGTRVRFI EPQSTLCAEP PDLQRLPVRE VPFREMTDHC LPLISPRSFP PSLQVASGES MVLHCRALAE PEPEIYWVTP AGLRLTPAHA GRRYRVYPEG TLELRRVTAE EAGLYTCVAQ NLVGADTKTV SVVVGRALLQ PGRDEGQGLE LRVQETHPYH ILLSWVTPPN TVSTNLTWSS ASSLRGQGAT ALARLPRGTH SYNITRLLQA TEYWACLQVA FADAHTQLAC VWARTKEATS CHRALGDRPG

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

78,859 Da

Sequence Positions

19-630

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

605492

3D Structure

ModBase 3D Structure for O75325

Species

Homo sapiens (Human)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of LRRN2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LRRN2. It may not necessarily be applicable to this product.

NCBI GI #

42544231

NCBI GeneID

10446

NCBI Accession #

NP_006329.2

UniProt Primary Accession #

O75325

UniProt Secondary Accession #

Q5T0Y0; Q6UXM0; Q8N182; B2R624

UniProt Related Accession #

O75325

GenBank Nucleotide #

NM_006338.2

NCBI Official Full Name

leucine-rich repeat neuronal protein 2

NCBI Official Synonym Full Names

leucine rich repeat neuronal 2

NCBI Official Symbol

LRRN2

NCBI Official Synonym Symbols

GAC1; LRRN5; LRANK1; FIGLER7

UniProt Protein Name

Leucine-rich repeat neuronal protein 2

UniProt Synonym Protein Names

Glioma amplified on chromosome 1 protein; Leucine-rich repeat neuronal protein 5

Protein Family

Leucine-rich repeat neuronal protein

UniProt Gene Name

LRRN2

UniProt Synonym Gene Names

GAC1; LRRN5

UniProt Entry Name

LRRN2_HUMAN

NCBI Protein Information

leucine-rich repeat neuronal protein 2; leucine rich repeat neuronal 5; leucine rich and ankyrin repeats 1; leucine-rich repeat neuronal protein 5; glioma amplified on chromosome 1 protein; fibronectin type III, immunoglobulin and leucine rich repeat domain 7

NCBI Summary for LRRN2

The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for LRRN2

LRRN2:

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: integral to membrane

Molecular Function: receptor activity

Biological Process: signal transduction; cell adhesion

Research Articles on LRRN2

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with LRRN2 recombinant protein

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>3 publications with LRRN2 and Brain Diseases
Nervous System Diseases Antibodies	>3 publications with LRRN2 and Nervous System Diseases
Cognition Disorders Antibodies	>1 publications with LRRN2 and Cognition Disorders
Inflammation Antibodies	>1 publications with LRRN2 and Inflammation
Disease Models, Animal Antibodies	>1 publications with LRRN2 and Disease Models, Animal

Organs/Tissues associated with LRRN2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>3 publications with LRRN2 and Brain