Rabbit MIP Recombinant Protein – Cat# MBS1086405

Lens Fiber Major Intrinsic Protein (MIP) Rabbit Recombinant Protein

Name: MIP Recombinant Protein; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS1086405
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1086405

MBS1086405 is a recombinant protein targeting MIP. Also known as Recombinant Rabbit Lens fiber major intrinsic protein (MIP). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Lens fiber major intrinsic protein (MIP), Recombinant Protein

Full Product Name

Recombinant Rabbit Lens fiber major intrinsic protein (MIP)

Product Gene Name

MIP recombinant protein

Product Synonym Gene Name

MIP

Product Synonym Names

Recombinant Lens fiber major intrinsic protein (MIP); Lens fiber major intrinsic protein; Aquaporin-0

Sequence

MWELRSASFW RAIFAEFFAT LFYVFFGLGA SLRWAPGPLH VLQVALAFGL ALATLVQAVG HISGAHVNPA VTFAFLVGSQ MSLLRAICYM AAQLLGAVAG AAVLYSVTPA AVRGNLALNT LHPGVSLGQA TTVEIFLTLQ FVLCIFATYD ERRNGRLGSV ALAVGFSLTL GHLFGMYYTG AGMNPARSFA PAILTRNFTN HWVYWVGPII GGGLASLLYD FLLFPRLKSV SERLSILKGA RPSDSNGQPE GTGEPVELKT QAL

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

28,171 Da

Sequence Positions

1-263

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: 4; NC_013672.1 (39983326..39987288, complement). Location: chromosome: 4

3D Structure

ModBase 3D Structure for A4L9J0

Species

Oryctolagus cuniculus (Rabbit)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of MIP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MIP. It may not necessarily be applicable to this product.

NCBI GI #

153792099

NCBI GeneID

100101574

NCBI Accession #

NP_001093431.1

UniProt Primary Accession #

A4L9J0

UniProt Related Accession #

A4L9J0

GenBank Nucleotide #

NM_001099961.1

NCBI Official Full Name

lens fiber major intrinsic protein

NCBI Official Symbol

MIP

UniProt Protein Name

Lens fiber major intrinsic protein

UniProt Synonym Protein Names

Aquaporin-0

Protein Family

Allatostatins

UniProt Gene Name

MIP

UniProt Entry Name

MIP_RABIT

NCBI Protein Information

lens fiber major intrinsic protein; aquaporin; aquaporin-0

UniProt Comments for MIP

Function: Water channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core

By similarity.

Subunit structure: Homotetramer. Homooctamer formed by head-to-head interaction between homotetramers from adjoining membranes

By similarity.

Subcellular location: Membrane; Multi-pass membrane protein

By similarity. Cell junction › gap junction

By similarity.

Domain: Aquaporins contain two tandem repeats each containing two membrane-spanning helices and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA). Each tandem repeat contains a loop and a short helix that enter and leave the lipid bilayer on the same side

By similarity.

Post-translational modification: Subject to partial proteolytic cleavage in the eye lens core. Partial proteolysis promotes interactions between tetramers from adjoining membranes

By similarity.

Sequence similarities: Belongs to the MIP/aquaporin (TC 1.A.8) family. [View classification]

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with MIP recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>1968 publications with MIP and Inflammation
Necrosis Antibodies	>1423 publications with MIP and Necrosis
Neoplasms Antibodies	>801 publications with MIP and Neoplasms
Cardiovascular Diseases Antibodies	>758 publications with MIP and Cardiovascular Diseases
Disease Models, Animal Antibodies	>650 publications with MIP and Disease Models, Animal
Respiratory Tract Infections Antibodies	>424 publications with MIP and Respiratory Tract Infections
Liver Diseases Antibodies	>237 publications with MIP and Liver Diseases
Gastrointestinal Diseases Antibodies	>223 publications with MIP and Gastrointestinal Diseases
Sepsis Antibodies	>208 publications with MIP and Sepsis
Heart Diseases Antibodies	>169 publications with MIP and Heart Diseases

Organs/Tissues associated with MIP recombinant protein

Organ/Tissue Name	Pubmed Publications
Eye Antibodies	>330 publications with MIP and Eye