Microtubule-Associated Tumor Suppressor 1 (MTUS1) ELISA Kit for Rat

Name: Rat MTUS1 ELISA Kit; Microtubule-Associated Tumor Suppressor 1; MyBioSource
Brand: MyBioSource
SKU: MBS109571
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS109571

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used to determine the level of MTUS1 (hereafter termed "analyte") in undiluted original Camel body fluids and tissue homogenates.… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Microtubule-Associated Tumor Suppressor 1 (MTUS1), ELISA Kit

Full Product Name

Rat Microtubule-Associated Tumor Suppressor 1 (MTUS1) ELISA Kit

Product Gene Name

MTUS1 elisa kit

Species Reactivity

Rat

Assay Type

Quantitative Sandwich

Samples

Camel Body Fluids And Tissue Homogenates

Detection Range

0.25ng/ml-8ng/ml

Sensitivity

0.1ng/ml.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%

Molecular Weight

135,661 Da

3D Structure

ModBase 3D Structure for Q9ULD2

Other Notes

Small volumes of MTUS1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MTUS1 purchase

MBS109571 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Microtubule-Associated Tumor Suppressor 1 (MTUS1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MTUS1. The ELISA analytical biochemical technique of the MBS109571 kit is based on MTUS1 antibody-MTUS1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MTUS1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MTUS1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for MTUS1. It may not necessarily be applicable to this product.

NCBI GI #

1386876321

NCBI GeneID

57509

NCBI Accession #

NP_001349988.1

UniProt Primary Accession #

Q9ULD2

UniProt Secondary Accession #

Q63HJ6; Q659F4; Q6PK49; Q6URW7; Q8N4M6; A8K135; B2RBJ6; B3KWJ9; B4DH03; B9EGA1; D3DSP8

UniProt Related Accession #

Q9ULD2

GenBank Nucleotide #

NM_001363059.1

NCBI Official Full Name

microtubule-associated tumor suppressor 1 isoform 1

NCBI Official Synonym Full Names

microtubule associated scaffold protein 1

NCBI Official Symbol

MTUS1

NCBI Official Synonym Symbols

ATBP; ATIP; ICIS; MP44; ATIP3; MTSG1

UniProt Protein Name

Microtubule-associated tumor suppressor 1

UniProt Synonym Protein Names

AT2 receptor-binding protein; Angiotensin-II type 2 receptor-interacting protein; Mitochondrial tumor suppressor 1

Protein Family

Microtubule-associated tumor suppressor

UniProt Gene Name

MTUS1

UniProt Synonym Gene Names

ATBP; ATIP; GK1; KIAA1288; MTSG1

NCBI Protein Information

microtubule-associated tumor suppressor 1

NCBI Summary for MTUS1

This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]

UniProt Comments for MTUS1

Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.

Research Articles on MTUS1

1. MTUS1 is not only involved in the formation and progression of human cancers but also involved in the complex pathological conditions such as cardiac hypertrophy, atherosclerosis, and SLE-like lymphoproliferative diseases. Several molecular mechanisms such as proliferation, differentiation, DNA repair, inflammation, vascular remodeling and senescence appear to be tightly regulated by the MTUS1-encoded proteins.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MTUS1 elisa kit

Reference Product	PubMed Publications
AGTR2 elisa kit	>14 publications with MTUS1 and AGTR2
FGF2 elisa kit	>1 publications with MTUS1 and FGF2

Diseases associated with MTUS1 elisa kit

Disease Name	Pubmed Publications
Neoplasm Metastasis Antibodies	>7 publications with MTUS1 and Neoplasm Metastasis
Breast Neoplasms Antibodies	>7 publications with MTUS1 and Breast Neoplasms
Cardiovascular Diseases Antibodies	>6 publications with MTUS1 and Cardiovascular Diseases
Hypertrophy Antibodies	>5 publications with MTUS1 and Hypertrophy
Carcinoma, Squamous Cell Antibodies	>5 publications with MTUS1 and Carcinoma, Squamous Cell
Heart Diseases Antibodies	>5 publications with MTUS1 and Heart Diseases
Disease Models, Animal Antibodies	>4 publications with MTUS1 and Disease Models, Animal
Inflammation Antibodies	>4 publications with MTUS1 and Inflammation
Hypertension Antibodies	>3 publications with MTUS1 and Hypertension
Adenocarcinoma Antibodies	>3 publications with MTUS1 and Adenocarcinoma

Organs/Tissues associated with MTUS1 elisa kit

Organ/Tissue Name	Pubmed Publications
Vascular Antibodies	>9 publications with MTUS1 and Vascular
Lung Antibodies	>6 publications with MTUS1 and Lung
Blood Antibodies	>5 publications with MTUS1 and Blood
Brain Antibodies	>5 publications with MTUS1 and Brain
Prostate Antibodies	>4 publications with MTUS1 and Prostate
Bladder Antibodies	>4 publications with MTUS1 and Bladder
Muscle Antibodies	>4 publications with MTUS1 and Muscle
Heart Antibodies	>4 publications with MTUS1 and Heart
Skin Antibodies	>3 publications with MTUS1 and Skin
Liver Antibodies	>3 publications with MTUS1 and Liver