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Immunoglobulin Superfamily Member 8 (IGSF8) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS109630

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used to determine the level of IGSF8 (hereafter termed "analyte") in undiluted original Fish body fluids and tissue homogenates.… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Immunoglobulin Superfamily Member 8 (IGSF8), ELISA Kit
Full Product Name
Human Immunoglobulin Superfamily Member 8 (IGSF8) ELISA Kit
Product Gene Name
IGSF8 elisa kit
Species Reactivity
Human
Assay Type
Quantitative Sandwich
Samples
Fish Body Fluids And Tissue Homogenates
Detection Range
25ug/ml-800ug/ml
Sensitivity
2.0ug/ml.
Preparation and Storage
Store all reagents at 2-8 degree C
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
Intra-assay Precision
Intra-assay CV (%) is less than 15%
Molecular Weight
40,191 Da
3D Structure
ModBase 3D Structure for Q969P0

Other Notes

Small volumes of IGSF8 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IGSF8 purchase

MBS109630 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Immunoglobulin Superfamily Member 8 (IGSF8) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IGSF8. The ELISA analytical biochemical technique of the MBS109630 kit is based on IGSF8 antibody-IGSF8 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IGSF8 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IGSF8. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for IGSF8. It may not necessarily be applicable to this product.

NCBI GI #
16445029
NCBI GeneID
93185
NCBI Accession #
NP_443100.1
UniProt Primary Accession #
Q969P0
UniProt Secondary Accession #
Q8NG09; Q96DP4; Q9BTG9
UniProt Related Accession #
Q969P0
GenBank Nucleotide #
NM_052868.6
NCBI Official Full Name
immunoglobulin superfamily member 8
NCBI Official Synonym Full Names
immunoglobulin superfamily member 8
NCBI Official Symbol
IGSF8
NCBI Official Synonym Symbols
EWI2; PGRL; CD316; EWI-2; KCT-4; CD81P3; LIR-D1
UniProt Protein Name
Immunoglobulin superfamily member 8
UniProt Synonym Protein Names
CD81 partner 3; Glu-Trp-Ile EWI motif-containing protein 2; EWI-2; Keratinocytes-associated transmembrane protein 4; KCT-4; LIR-D1; Prostaglandin regulatory-like protein; PGRL; CD_antigen: CD316
Protein Family
Immunoglobulin superfamily
UniProt Gene Name
IGSF8
UniProt Synonym Gene Names
CD81P3; EWI2; KCT4; IgSF8; EWI-2; KCT-4; PGRL
NCBI Protein Information
immunoglobulin superfamily member 8

NCBI Summary for IGSF8

This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]
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UniProt Comments for IGSF8

May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
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Research Articles on IGSF8

1. EWI-2 negatively regulates TGF-beta signaling and its downstream events including cytostasis (in vitro and in vivo), EMT-like changes, cell migration, CD271-dependent invasion, and lung metastasis (in vivo).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IGSF8 elisa kit

 Reference Product  PubMed Publications
 CD9 elisa kit  >17 publications with IGSF8 and CD9
 CD81 elisa kit  >16 publications with IGSF8 and CD81
 CD82 elisa kit  >2 publications with IGSF8 and CD82

Diseases associated with IGSF8 elisa kit

 Disease Name  Pubmed Publications
 Hepatitis Antibodies  >4 publications with IGSF8 and Hepatitis
 Liver Diseases Antibodies  >1 publications with IGSF8 and Liver Diseases

Organs/Tissues associated with IGSF8 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with IGSF8 and Blood
 Vascular Antibodies  >4 publications with IGSF8 and Vascular
 Kidney Antibodies  >2 publications with IGSF8 and Kidney
 Embryonic Tissue Antibodies  >2 publications with IGSF8 and Embryonic Tissue
 Brain Antibodies  >2 publications with IGSF8 and Brain
 Ganglia Antibodies  >1 publications with IGSF8 and Ganglia
 Nerve Antibodies  >1 publications with IGSF8 and Nerve
 Lymph Antibodies  >1 publications with IGSF8 and Lymph
 Prostate Antibodies  >1 publications with IGSF8 and Prostate
 Lung Antibodies  >1 publications with IGSF8 and Lung
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