Human HIST1H1C ELISA Kit – Cat# MBS109634

Histone H1.2 (HIST1H1C) ELISA Kit for Human

Name: Human HIST1H1C ELISA Kit; Histone H1.2; MyBioSource
Brand: MyBioSource
SKU: MBS109634
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS109634

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used to determine the level of HIST1H1C (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates.… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Histone H1.2 (HIST1H1C), ELISA Kit

Full Product Name

Human Histone H1.2 (HIST1H1C) ELISA Kit

Product Gene Name

HIST1H1C elisa kit

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Samples

Human Body Fluids And Tissue Homogenates

Detection Range

0.25ng/ml-8ng/ml

Sensitivity

0.1ng/ml.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%

Molecular Weight

21,365 Da

3D Structure

ModBase 3D Structure for P16403

Other Notes

Small volumes of HIST1H1C elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HIST1H1C purchase

MBS109634 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Histone H1.2 (HIST1H1C) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HIST1H1C. The ELISA analytical biochemical technique of the MBS109634 kit is based on HIST1H1C antibody-HIST1H1C antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HIST1H1C antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HIST1H1C. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for HIST1H1C. It may not necessarily be applicable to this product.

NCBI GI #

4885375

NCBI GeneID

3006

NCBI Accession #

NP_005310.1

UniProt Primary Accession #

P16403

UniProt Secondary Accession #

A8K4I2

UniProt Related Accession #

P16403

GenBank Nucleotide #

NM_005319.3

NCBI Official Full Name

histone H1.2

NCBI Official Synonym Full Names

histone cluster 1 H1 family member c

NCBI Official Symbol

HIST1H1C

NCBI Official Synonym Symbols

H1C; H1.2; H1F2; H1s-1

UniProt Protein Name

Histone H1.2

UniProt Synonym Protein Names

Histone H1c; Histone H1d; Histone H1s-1

UniProt Gene Name

HIST1H1C

UniProt Synonym Gene Names

H1F2

NCBI Protein Information

histone H1.2

NCBI Summary for HIST1H1C

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]

UniProt Comments for HIST1H1C

Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation ().

Research Articles on HIST1H1C

1. results define a network of E2F target genes as susceptible to the regulatory influence of H1.2, where H1.2 augments global association of pRb with chromatin, enhances transcriptional repression by pRb, and facilitates pRb-dependent cell-cycle arrest

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HIST1H1C elisa kit

Reference Product	PubMed Publications
CDK1 elisa kit	>1 publications with HIST1H1C and CDK1

Pathways associated with HIST1H1C elisa kit

Products by Pathway	Pathway Diagram
Activation Of DNA Fragmentation Factor Pathway antibodies	Activation Of DNA Fragmentation Factor Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptosis Induced DNA Fragmentation Pathway antibodies	Apoptosis Induced DNA Fragmentation Pathway Diagram
Apoptotic Execution Phase Pathway antibodies	Apoptotic Execution Phase Pathway Diagram
Cellular Senescence Pathway antibodies	Cellular Senescence Pathway Diagram
Cellular Responses To Stress Pathway antibodies	Cellular Responses To Stress Pathway Diagram
DNA Damage/Telomere Stress Induced Senescence Pathway antibodies	DNA Damage/Telomere Stress Induced Senescence Pathway Diagram
Formation Of Senescence-Associated Heterochromatin Foci (SAHF) Pathway antibodies	Formation Of Senescence-Associated Heterochromatin Foci (SAHF) Pathway Diagram
Programmed Cell Death Pathway antibodies	Programmed Cell Death Pathway Diagram

Diseases associated with HIST1H1C elisa kit

Disease Name	Pubmed Publications
Heart Failure Antibodies	>1 publications with HIST1H1C and Heart Failure
Leukemia Antibodies	>1 publications with HIST1H1C and Leukemia
Heart Diseases Antibodies	>1 publications with HIST1H1C and Heart Diseases
Pancreatic Neoplasms Antibodies	>1 publications with HIST1H1C and Pancreatic Neoplasms
Kidney Diseases Antibodies	>1 publications with HIST1H1C and Kidney Diseases

Organs/Tissues associated with HIST1H1C elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>2 publications with HIST1H1C and Blood
Kidney Antibodies	>1 publications with HIST1H1C and Kidney
Heart Antibodies	>1 publications with HIST1H1C and Heart
Pancreas Antibodies	>1 publications with HIST1H1C and Pancreas
Bone Antibodies	>1 publications with HIST1H1C and Bone