Ets Domain-Containing Protein Elk-3 (ELK3) ELISA Kit for Human

Name: Human ELK3 ELISA Kit; Ets Domain-Containing Protein Elk-3; MyBioSource
Brand: MyBioSource
SKU: MBS109650
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS109650

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used to determine the level of ELK3 (hereafter termed "analyte") in… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Ets Domain-Containing Protein Elk-3 (ELK3), ELISA Kit

Full Product Name

Human Ets Domain-Containing Protein Elk-3 (ELK3) ELISA Kit

Product Gene Name

ELK3 elisa kit

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Detection Range

3.12ng/ml-100ng/ml

Sensitivity

1.0ng/ml

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

44,240 Da

3D Structure

ModBase 3D Structure for P41970

Other Notes

Small volumes of ELK3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ELK3 purchase

MBS109650 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Ets Domain-Containing Protein Elk-3 (ELK3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ELK3. The ELISA analytical biochemical technique of the MBS109650 kit is based on ELK3 antibody-ELK3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ELK3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ELK3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for ELK3. It may not necessarily be applicable to this product.

NCBI GI #

44955921

NCBI GeneID

2004

NCBI Accession #

NP_005221.2

UniProt Primary Accession #

P41970

UniProt Secondary Accession #

Q6FG57; Q6GU29; Q9UD17; B2R6S6

UniProt Related Accession #

P41970

GenBank Nucleotide #

NM_005230.4

NCBI Official Full Name

ETS domain-containing protein Elk-3 isoform 1

NCBI Official Synonym Full Names

ELK3, ETS transcription factor

NCBI Official Symbol

ELK3

NCBI Official Synonym Symbols

ERP; NET; SAP2; SAP-2

UniProt Protein Name

ETS domain-containing protein Elk-3

UniProt Synonym Protein Names

ETS-related protein ERP; ETS-related protein NET; Serum response factor accessory protein 2; SAP-2; SRF accessory protein 2

Protein Family

ETS domain-containing protein

UniProt Gene Name

ELK3

UniProt Synonym Gene Names

NET; SAP2; SAP-2; SRF accessory protein 2

NCBI Protein Information

ETS domain-containing protein Elk-3

NCBI Summary for ELK3

This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

UniProt Comments for ELK3

May be a negative regulator of transcription, but can activate transcription when coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum response factor and the ETS and SRF motifs of the Fos serum response element.

Research Articles on ELK3

1. Study demonstrates that miR-135a regulates cell proliferation in breast cancer by targeting ELK1 and ELK3 oncogenes, and suggests that miR-135a potentially can act as a tumor suppressor.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ELK3 elisa kit

Reference Product	PubMed Publications
TCF3 elisa kit	>1 publications with ELK3 and TCF3

Pathways associated with ELK3 elisa kit

Products by Pathway	Pathway Diagram
Id Signaling Pathway antibodies	Id Signaling Pathway Diagram

Diseases associated with ELK3 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>23 publications with ELK3 and Neoplasms
Disease Models, Animal Antibodies	>8 publications with ELK3 and Disease Models, Animal
Neoplasms, Experimental Antibodies	>5 publications with ELK3 and Neoplasms, Experimental
Heart Diseases Antibodies	>4 publications with ELK3 and Heart Diseases
Nervous System Diseases Antibodies	>4 publications with ELK3 and Nervous System Diseases
Adenocarcinoma Antibodies	>3 publications with ELK3 and Adenocarcinoma
Lung Diseases Antibodies	>3 publications with ELK3 and Lung Diseases
Breast Neoplasms Antibodies	>3 publications with ELK3 and Breast Neoplasms
Liver Diseases Antibodies	>2 publications with ELK3 and Liver Diseases
Liver Neoplasms Antibodies	>2 publications with ELK3 and Liver Neoplasms

Organs/Tissues associated with ELK3 elisa kit

Organ/Tissue Name	Pubmed Publications
Vascular Antibodies	>11 publications with ELK3 and Vascular
Brain Antibodies	>10 publications with ELK3 and Brain
Heart Antibodies	>8 publications with ELK3 and Heart
Lung Antibodies	>8 publications with ELK3 and Lung
Embryonic Tissue Antibodies	>6 publications with ELK3 and Embryonic Tissue
Muscle Antibodies	>5 publications with ELK3 and Muscle
Liver Antibodies	>5 publications with ELK3 and Liver
Prostate Antibodies	>4 publications with ELK3 and Prostate
Eye Antibodies	>3 publications with ELK3 and Eye
Connective Tissue Antibodies	>3 publications with ELK3 and Connective Tissue