Rat MMP16 Recombinant Protein – Cat# MBS1102668

Matrix Metalloproteinase-16 (MMP16) Rat Recombinant Protein

Name: MMP16 Recombinant Protein; Matrix Metalloproteinase-16; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS1102668
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1102668

MBS1102668 is a recombinant protein targeting Mmp16. Also known as Recombinant Rat Matrix metalloproteinase-16 (Mmp16). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Matrix metalloproteinase-16 (Mmp16), Recombinant Protein

Full Product Name

Recombinant Rat Matrix metalloproteinase-16 (Mmp16)

Product Gene Name

Mmp16 recombinant protein

Product Synonym Names

Matrix metalloproteinase-16; MMP-16; EC=3.4.24.-; Membrane-type matrix metalloproteinase 3; MT-MMP 3; MTMMP3; Membrane-type-3 matrix metalloproteinase; MT3-MMP; MT3MMP

Sequence

Y ALTGQKWQHK HITYSIKNVT PKVGDPETRR AIRRAFDVWQ NVTPLTFEEV PYSELENGKR DVDITIIFAS GFHGDRSPFD GEGGFLAHAY FPGPGIGGDT HFDSDEPWTL GNPNHDGNDL FLVAVHELGH ALGLEHSNDP TAIMAPFYQY METDNFKLPN DDLQGIQKIY GPPDKIPPPT RPLPTVPPHR SVPPADPRKN DRPKPPRPPT GRPSYPGAKP NICDGNFNTL AILRREMFVF KDQWFWRVRN NRVMDGYPMQ ITYFWRGLPP SIDAVYENSD GNFVFFKGNK YWVFKDTTLQ PGYPHDLITL GNGIPPHGID SAIWWEDVGK TYFFKGDRYW RYSEEMKTMD PGYPKPITIW KGIPESPQGA FVHKENGFTY FYKGKEYWKF NNQILKVEPG YPRSILKDFM GCDGPTDRDK EGLSPPDDVD IVIKLDNTAS TVKA

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

62,775 Da

Sequence Positions

120-564

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for O35548

Species

Rattus norvegicus (Rat)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Mmp16 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Mmp16. It may not necessarily be applicable to this product.

NCBI GI #

18158443

NCBI GeneID

65205

NCBI Accession #

NP_542954.1

UniProt Primary Accession #

O35548

UniProt Secondary Accession #

O35541

UniProt Related Accession #

O35548

GenBank Nucleotide #

NM_080776.1

NCBI Official Full Name

matrix metalloproteinase-16

NCBI Official Synonym Full Names

matrix metallopeptidase 16

NCBI Official Symbol

Mmp16

NCBI Official Synonym Symbols

Mt3-mmp

UniProt Protein Name

Matrix metalloproteinase-16

UniProt Synonym Protein Names

Membrane-type matrix metalloproteinase 3; MT-MMP 3; MTMMP3; Membrane-type-3 matrix metalloproteinase; MT3-MMP; MT3MMP

Protein Family

Matrix metalloproteinase

UniProt Gene Name

Mmp16

UniProt Synonym Gene Names

MMP-16; MT-MMP 3; MTMMP3; MT3-MMP; MT3MMP

UniProt Entry Name

MMP16_RAT

NCBI Protein Information

matrix metalloproteinase-16; MMP-16; MT3MMP; MTMMP3; MT-MMP 3; matrix metalloproteinase 16; membrane-type matrix metalloproteinase 3; membrane-type-3 matrix metalloproteinase

NCBI Summary for Mmp16

membrane type matrix metalloproteinase; may be involved in matrix remodeling of blood vessels [RGD, Feb 2006]

UniProt Comments for Mmp16

MMP16: Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells. Belongs to the peptidase M10A family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease; Membrane protein, integral; EC 3.4.24.-

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; plasma membrane; integral to membrane

Molecular Function: zinc ion binding; metalloendopeptidase activity; calcium ion binding

Biological Process: collagen catabolic process; ossification; embryonic cranial skeleton morphogenesis; proteolysis; endochondral ossification

Research Articles on Mmp16

1. MMP16 polymorphisms appear to influence not only the pulmonary expression and function of MMP16 but also the risk of bronchopulmonary dysplasia

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Mmp16 recombinant protein

Products by Pathway	Pathway Diagram
Activation Of Matrix Metalloproteinases Pathway antibodies	Activation Of Matrix Metalloproteinases Pathway Diagram
Degradation Of The Extracellular Matrix Pathway antibodies	Degradation Of The Extracellular Matrix Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram
Matrix Metalloproteinases Pathway antibodies	Matrix Metalloproteinases Pathway Diagram
MicroRNAs In Cancer Pathway antibodies	MicroRNAs In Cancer Pathway Diagram
MicroRNAs In Cancer Pathway antibodies	MicroRNAs In Cancer Pathway Diagram

Diseases associated with Mmp16 recombinant protein

Disease Name	Pubmed Publications
Neoplasm Metastasis Antibodies	>8 publications with Mmp16 and Neoplasm Metastasis
Breast Neoplasms Antibodies	>5 publications with Mmp16 and Breast Neoplasms
Adenocarcinoma Antibodies	>5 publications with Mmp16 and Adenocarcinoma
Fibrosis Antibodies	>4 publications with Mmp16 and Fibrosis
Nervous System Diseases Antibodies	>3 publications with Mmp16 and Nervous System Diseases
Cardiovascular Diseases Antibodies	>3 publications with Mmp16 and Cardiovascular Diseases
Hypertension Antibodies	>2 publications with Mmp16 and Hypertension
Ovarian Neoplasms Antibodies	>2 publications with Mmp16 and Ovarian Neoplasms
Glioblastoma Antibodies	>2 publications with Mmp16 and Glioblastoma
Prostatic Neoplasms Antibodies	>2 publications with Mmp16 and Prostatic Neoplasms

Organs/Tissues associated with Mmp16 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>8 publications with Mmp16 and Brain
Lung Antibodies	>7 publications with Mmp16 and Lung
Heart Antibodies	>3 publications with Mmp16 and Heart
Embryonic Tissue Antibodies	>3 publications with Mmp16 and Embryonic Tissue
Connective Tissue Antibodies	>3 publications with Mmp16 and Connective Tissue