Drosophila Melanogaster FUR1 Recombinant Protein – Cat# MBS1117286

Furin-Like Protease 1, Isoform 1-CRR (FUR1) Drosophila Melanogaster Recombinant Protein

Name: FUR1 Recombinant Protein; Drosophila Melanogaster; MyBioSource
Brand: MyBioSource
SKU: MBS1117286
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1117286

MBS1117286 is a recombinant protein targeting Fur1. Also known as Recombinant Drosophila melanogaster Furin-like protease 1, isoform 1-CRR (Fur1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Furin-like protease 1, isoform 1-CRR (Fur1), Recombinant Protein

Full Product Name

Recombinant Drosophila melanogaster Furin-like protease 1, isoform 1-CRR (Fur1)

Product Gene Name

Fur1 recombinant protein

Product Synonym Gene Name

Fur1; CG10772

Product Synonym Names

Recombinant Furin-like protease 1, isoform 1-CRR (Fur1); Furin-like protease 1, isoform 1-CRR; Furin-1 EC= 3.4.21.75; Kex2-like endoprotease 1 dKLIP-1

Sequence

DFIRMRPSRT SSRAMSMVDA MSFNDSKWPQ MWYLNRGGGL DMNVIPAWKM GITGKGVVVT ILDDGLESDH PDIQDNYDPK ASYDVNSHDD DPMPHYDMTD SNRHGTRCAG EVAATANNSF CAVGIAYGAS VGGVRMLDGD VTDAVEARSL SLNPQHIDIY SASWGPDDDG KTVDGPGELA SRAFIEGTTK GRGGKGSIFI WASGNGGREQ DNCNCDGYTN SIWTLSISSA TEEGHVPWYS EKCSSTLATT YSSGGQGEKQ VVTTDLHHSC TVSHTGTSAS APLAAGIAAL VLQSNQNLTW RDLQHIVVRT AKPANLKDPS WSRNGVGRRV SHSFGYGLMD AAEMVRVARN WKAVPEQQRC EINAPHVDKV IPPRTHITLQ LTVNHCRSVN YLEHVQAKIT LTSQRRGDIQ LFLRSPANTS VTLLTPRIHD NSRSGFNQWP FMSVHTWGES PQGNWQLEIH NEGRYMAQIT QWDMIFYGTE TPAQPDDVAN PSQSNQFNLY GNDMAHNDVE YDSTGQWRNM QQVGEVGMTR DHSNTAACLK WSDRKCLECN DSAYMFEDQC YDVCPVHTYP LDKFQAEEDE QDDEVTRGPV NPYSSSPMDH SLLMSNSLDD KQDPLQAEDR RRRSSLTQLV EVPSRVCAAC DRSCLECYGA LASQCSTCSP GSQLRKILNE TFCYAYVVRS TGMASVVDIS KMDDRDTQQY MTGTTVLLLV SVIFTLMGVA VAGGIVYHRR AMARSNELYS RVSLVPGDES DSDEDELFTA HFPARKSGVN IYRDEAPSEK IFEEDEISHL VP

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

120,993 Da

Sequence Positions

310-1101

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: 3R; NT_033777.2 (21173090..21298778, complement). Location: 96D2-96E1

3D Structure

ModBase 3D Structure for P30430

Species

Drosophila melanogaster (Fruit fly)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Fur1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Fur1. It may not necessarily be applicable to this product.

NCBI GI #

24650056

NCBI GeneID

47220

NCBI Accession #

NP_733102.1

UniProt Primary Accession #

P30430

UniProt Secondary Accession #

Q27235; Q9VBR5

UniProt Related Accession #

AAA28545

GenBank Nucleotide #

NM_170654.1

NCBI Official Full Name

furin 1, isoform A

NCBI Official Synonym Full Names

Furin 1

NCBI Official Symbol

Fur1

NCBI Official Synonym Symbols

CG10772; dFur1; Dfur1; dFurin 1; Dfurin1; dKLIP-1; DmelCG10772; fur-1; fur1; furin; Furin; Furl; fur[1]; Klip1; l(3)rL205

UniProt Protein Name

Furin-like protease 1, isoform 1-CRR

UniProt Synonym Protein Names

Kex2-like endoprotease 1; dKLIP-1

Protein Family

Ferric uptake regulation protein

UniProt Gene Name

Fur1

UniProt Synonym Gene Names

Furin-1

UniProt Entry Name

FUR1C_DROME

NCBI Protein Information

CG10772 gene product from transcript CG10772-RA; CG10772-PA; CG10772-PB; CG10772-PC; CG10772-PD; CG10772-PE; CG10772-PF; Dfurin1; Fur1-PA; Fur1-PB; Fur1-PC; Fur1-PD; Fur1-PE; Fur1-PF; Furin-like protease; furin 1

UniProt Comments for Fur1

Function: Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif

By similarity.

Catalytic activity: Release of mature proteins from their proproteins by cleavage of -Arg-Xaa-Yaa-Arg-|-Zaa- bonds, where Xaa can be any amino acid and Yaa is Arg or Lys. Releases albumin, complement component C3 and vWF from their respective precursors.

Subcellular location: Golgi apparatus membrane; Multi-pass membrane protein Ref.2.

Tissue specificity: In adults, isoform 1-CRR is expressed in CNS, fat body, and female reproductive tissues, and in embryos, in anal pads, hindgut, developing antennomaxillary complex, oenocytes, clipeolabrum, pharynx, trachea, CNS and developing posterior spiracles. Ref.2

Developmental stage: Isoform 1-CRR is expressed in embryos, larvae, pupae and adults. Ref.2

Sequence similarities: Belongs to the peptidase S8 family. Furin subfamily.

Research Articles on Fur1

1. alternative PE2 cleavage phenotypes observed in vertebrate and arthropod cells were due to differences in substrate specificity between the arthropod and vertebrate furin

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Fur1 recombinant protein

Products by Pathway	Pathway Diagram
Pre-NOTCH Expression And Processing Pathway antibodies	Pre-NOTCH Expression And Processing Pathway Diagram
Pre-NOTCH Processing In Golgi Pathway antibodies	Pre-NOTCH Processing In Golgi Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By NOTCH Pathway antibodies	Signaling By NOTCH Pathway Diagram

Diseases associated with Fur1 recombinant protein

Disease Name	Pubmed Publications
Carcinoma Antibodies	>2 publications with Fur1 and Carcinoma
Inflammation Antibodies	>1 publications with Fur1 and Inflammation

Organs/Tissues associated with Fur1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Fat Body Antibodies	>1 publications with Fur1 and Fat Body