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Fibroblast Growth Factor Receptor Substrate 3 (FRS3) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1118843

This protein is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras. More details

$1290 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Fibroblast growth factor receptor substrate 3 (FRS3), Recombinant Protein
Full Product Name
Recombinant Human Fibroblast growth factor receptor substrate 3 (FRS3)
Product Gene Name
Sequence
GSCCSCLNRD SVPDNHPTKF KVTNVDDEGV ELGSGVMELT QSELVLHLHR REAVRWPYLC LRRYGYDSNL FSFESGRRCQ TGQGIFAFKC SRAEEIFNLL QDLMQCNSIN VMEEPVIITR NSHPAELDLP RAPQPPNALG YTVSSFSNGC PGEGPRFSAP RRLSTSSLRH PSLGEESTHA LIAPDEQSHT YVNTPASEDD HRRGRHCLQP LPEGQAPFLP QARGPDQRDP QVFLQPGQVK FVLGPTPARR HMVKCQGLCP SLHDPPHHNN NNEAPSECPA QPKCTYENVT GGLWRGAGWR LSPEEPGWNG LAHRRAALLH YENLPPLPPV WESQAQQLGG EAGDDGDSRD GLTPSSNGFP DGEEDETPLQ KPTSTRAAIR SHGSFPVPLT RRRGSPRVFN FDFRRPGPEP PRQLNYIQVE LKGWGGDRPK GPQNPSSPQA PMPTTHPARS SDSYAVIDLK KTVAMSNLQR ALPRDDGTAR KTRHNSTDLP L
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
54,462 Da
Sequence Positions
2-492, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
607744
3D Structure
ModBase 3D Structure for O43559
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of FRS3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FRS3 purchase

MBS1118843 is a recombinant protein targeting FRS3. Also known as Recombinant Human Fibroblast growth factor receptor substrate 3 (FRS3). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for FRS3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
fibroblast growth factor receptor substrate 3
NCBI Official Synonym Full Names
fibroblast growth factor receptor substrate 3
NCBI Official Symbol
FRS3
NCBI Official Synonym Symbols
SNT2; FRS2B; SNT-2; FRS2beta; FRS2-beta
UniProt Protein Name
Fibroblast growth factor receptor substrate 3
UniProt Synonym Protein Names
FGFR-signaling adaptor SNT2; Suc1-associated neurotrophic factor target 2; SNT-2
UniProt Gene Name
FRS3
UniProt Synonym Gene Names
FGFR substrate 3; SNT-2
NCBI Protein Information
fibroblast growth factor receptor substrate 3

NCBI Summary for FRS3

This gene encodes a substrate for the fibroblast growth factor receptor. The encoded protein is found in the peripheral plasma membrane and links fibroblast growth factor receptor stimulation to activators of Ras. The encoded protein down-regulates extracellular regulated kinase 2 through direct binding. [provided by RefSeq, Jul 2013]
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UniProt Comments for FRS3

Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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