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Diphtheria Toxin (DT) Corynephage Beta Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1119041

MBS1119041 is a recombinant protein targeting DT. Also known as Recombinant Corynephage beta Diphtheria toxin, partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$835 / 0.05 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Diphtheria toxin (DT), Recombinant Protein
Full Product Name
Recombinant Corynephage beta Diphtheria toxin, partial
Product Gene Name
DT recombinant protein
Sequence
GADDVVDSSK SFVMENFSSY HGTKPGYVDS IQKGIQKPKS GTQGNYDDDW KGFYSTDNKY DAAGYSVDNE NPLSGKAGGV VKVTYPGLTK VLALKVDNAE TIKKELGLSL TEPLMEQVGT EEFIKRFGDG ASRVVLSLPF AEGSSSVEYI NNWEQAKALS VELEINFETR GKRGQDAMYE YMAQACAGNR VRR
Clone Number
E Coli or Yeast or Baculovirus or Mammalian Cell
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
61,602 Da
Sequence Positions
33-225. Partial,provide Diphtheria toxin fragment A Chain
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P00588
Species
Corynephage beta
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of DT recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DT. It may not necessarily be applicable to this product.

NCBI GI #
118949
NCBI Accession #
P00588.2
UniProt Primary Accession #
P00588
NCBI Official Full Name
Diphtheria toxin
UniProt Protein Name
Diphtheria toxin
UniProt Synonym Protein Names
NAD(+)--diphthamide ADP-ribosyltransferase (EC:2.4.2.36)
Protein Family
Diphtheria toxin
UniProt Gene Name
DT
UniProt Synonym Gene Names
DT

UniProt Comments for DT

Diphtheria toxin, produced by a phage infecting Corynebacterium diphtheriae, is a proenzyme that, after activation, catalyzes the covalent attachment of the ADP ribose moiety of NAD to eukaryotic elongation factor 2 (eEF-2). Fragment A is the catalytic portion responsible for enzymatic ADP-ribosylation of elongation factor 2, while fragment B is responsible for binding of toxin to cell receptors and entry of fragment A.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with DT recombinant protein

 Reference Product  PubMed Publications
 FLNA recombinant protein  >12 publications with DT and FLNA

Pathways associated with DT recombinant protein

 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram

Organs/Tissues associated with DT recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with DT and Bone
 Connective Tissue Antibodies  >4 publications with DT and Connective Tissue
 Heart Antibodies  >3 publications with DT and Heart
 Muscle Antibodies  >3 publications with DT and Muscle
 Brain Antibodies  >3 publications with DT and Brain
 Vascular Antibodies  >2 publications with DT and Vascular
 Embryonic Tissue Antibodies  >2 publications with DT and Embryonic Tissue
 Ear Antibodies  >1 publications with DT and Ear
 Kidney Antibodies  >1 publications with DT and Kidney
 Umbilical Cord Antibodies  >1 publications with DT and Umbilical Cord
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