Mouse ATF6B Recombinant Protein – Cat# MBS1125372

Cyclic AMP-Dependent Transcription Factor ATF-6 Beta (ATF6B) Mouse Recombinant Protein

Name: ATF6B Recombinant Protein; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS1125372
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1125372

MBS1125372 is a recombinant protein targeting Atf6b. Also known as Recombinant Mouse Cyclic AMP-dependent transcription factor ATF-6 beta (Atf6b). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Cyclic AMP-dependent transcription factor ATF-6 beta (Atf6b), Recombinant Protein

Full Product Name

Recombinant Mouse Cyclic AMP-dependent transcription factor ATF-6 beta (Atf6b)

Product Gene Name

Atf6b recombinant protein

Product Synonym Gene Name

Atf6b; Crebl1

Product Synonym Names

Cyclic AMP-dependent transcription factor ATF-6 beta; cAMP-dependent transcription factor ATF-6 beta; Activating transcription factor 6 beta; ATF6-beta; cAMP response element-binding protein-related protein; Creb-rp; cAMP-responsive element-binding protei

Sequence

AELMLLSEI ADPTRFFTDN LLSPEDWDST LYSGLDEVAE EQAQLFRCVE QDVPFDSSSL DVGMDVSPPE PPWDPLPIFP DLQVKSEPSS PCSSSSLSSE SSHLSTEPPS QVPGVGEVLH VKMESLAPPL CLLGDDPASP FETVQITVGS ASDDLSDIQT KLEPASPSSS VHSEASLLSA DSPSQPFIGE EVLEVKTESP SPPGCLLWDV PASSLGAVQI SMGPSPDSSS GKAPATRKPP LQPKPVVLTT VPVPPRAGPT SAAVLLQPLV QQPAVSPVVL IQGAIRVQPE GPAPAAPRPE RKSIVPAPMP GNSCPPEVDA KLLKRQQRMI KNRESACQSR RKKKEYLQGL EARLQAVLAD NQQLRRENAA LRRRLEALLA ENSGLKLGSG NRK

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

76,007 Da

Sequence Positions

2-393

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for O35451

Species

Mus musculus (Mouse)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Atf6b recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Atf6b. It may not necessarily be applicable to this product.

NCBI GI #

20137260

NCBI GeneID

12915

NCBI Accession #

O35451.1

UniProt Primary Accession #

O35451

UniProt Related Accession #

O35451

NCBI Official Full Name

Cyclic AMP-dependent transcription factor ATF-6 beta

NCBI Official Synonym Full Names

activating transcription factor 6 beta

NCBI Official Symbol

Atf6b

NCBI Official Synonym Symbols

Crebl1; Creb-rp; AA617266; ATF6beta

UniProt Protein Name

Cyclic AMP-dependent transcription factor ATF-6 beta

UniProt Synonym Protein Names

Activating transcription factor 6 beta; ATF6-beta; cAMP response element-binding protein-related protein; Creb-rp; cAMP-responsive element-binding protein-like 1Cleaved into the following chain:Processed cyclic AMP-dependent transcription factor ATF-6 beta

Protein Family

Cyclic AMP-dependent transcription factor

UniProt Gene Name

Atf6b

UniProt Synonym Gene Names

Crebl1; cAMP-dependent transcription factor ATF-6 beta; ATF6-beta; Creb-rp

UniProt Entry Name

ATF6B_MOUSE

NCBI Protein Information

cyclic AMP-dependent transcription factor ATF-6 beta; ATF6-beta; cAMP responsive element binding protein-like 1; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; cAMP response element binding protein-related protein; cAMP response element-binding protein-related protein

UniProt Comments for Atf6b

ATF6B: Transcriptional factor that acts in the unfolded protein response (UPR) pathway by activating UPR target genes induced during ER stress. Binds DNA on the 5'-CCAC[GA]-3' half of the ER stress response element (ERSE) (5'-CCAATN(9)CCAC[GA]-3') when NF-Y is bound to ERSE. Belongs to the bZIP family. ATF subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transcription factor

Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane; endomembrane system; integral to endoplasmic reticulum membrane; intracellular; nucleus

Molecular Function: DNA binding; sequence-specific DNA binding; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; regulation of transcription, DNA-dependent; unfolded protein response; response to unfolded protein

Research Articles on Atf6b

1. Toxoplasma virulence factor ROP18 inactivates host innate and adaptive immune responses by targeting ATF6beta.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Atf6b recombinant protein

Products by Pathway	Pathway Diagram
Adrenergic Signaling In Cardiomyocytes Pathway antibodies	Adrenergic Signaling In Cardiomyocytes Pathway Diagram
Adrenergic Signaling In Cardiomyocytes Pathway antibodies	Adrenergic Signaling In Cardiomyocytes Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Amphetamine Addiction Pathway antibodies	Amphetamine Addiction Pathway Diagram
Amphetamine Addiction Pathway antibodies	Amphetamine Addiction Pathway Diagram
Cocaine Addiction Pathway antibodies	Cocaine Addiction Pathway Diagram
Cocaine Addiction Pathway antibodies	Cocaine Addiction Pathway Diagram
Dopaminergic Synapse Pathway antibodies	Dopaminergic Synapse Pathway Diagram
Dopaminergic Synapse Pathway antibodies	Dopaminergic Synapse Pathway Diagram

Diseases associated with Atf6b recombinant protein

Disease Name	Pubmed Publications
Dementia Antibodies	>1 publications with Atf6b and Dementia
Cognition Disorders Antibodies	>1 publications with Atf6b and Cognition Disorders
Brain Diseases Antibodies	>1 publications with Atf6b and Brain Diseases
Mental Disorders Antibodies	>1 publications with Atf6b and Mental Disorders
Nervous System Diseases Antibodies	>1 publications with Atf6b and Nervous System Diseases

Organs/Tissues associated with Atf6b recombinant protein

Organ/Tissue Name	Pubmed Publications
Heart Antibodies	>2 publications with Atf6b and Heart
Other Antibodies	>1 publications with Atf6b and Other
Lung Antibodies	>1 publications with Atf6b and Lung
Brain Antibodies	>1 publications with Atf6b and Brain